Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety and efficacy of calcium d‐pantothenate and d‐panthenol for the renewal of its authorisation. Calcium d‐pantothenate and d‐panthenol are currently authorised as nutritional feed additives for all animal species and categories. The FEEDAP Panel concluded that the use of calcium d‐pantothenate and d‐panthenol as feed additive in animal nutrition under the conditions of use is of no concern for the safety of the target species, the consumer and the environment. Calcium d‐pantothenate is not irritant to skin and eyes and is not a dermal sensitiser. d‐panthenol is considered to be a skin and eye irritant and a dermal and respiratory sensitiser. There is no need for assessing the efficacy of the additive in the context of this renewal of the authorisation.