{"id":107727,"date":"2025-04-25T10:31:04","date_gmt":"2025-04-25T09:31:04","guid":{"rendered":"https:\/\/helloproject.es\/vigilancia\/safety-and-efficacy-of-a-feed-additive-consisting-of-l%e2%80%90lysine-sulfate-produced-with-corynebacterium-glutamicum-cgmcc-23982-for-all-animal-species-eppen-europa-sas-autoridad-europea-de-seguri\/"},"modified":"2025-04-25T10:31:04","modified_gmt":"2025-04-25T09:31:04","slug":"safety-and-efficacy-of-a-feed-additive-consisting-of-l%e2%80%90lysine-sulfate-produced-with-corynebacterium-glutamicum-cgmcc-23982-for-all-animal-species-eppen-europa-sas-autoridad-europea-de-seguri","status":"publish","type":"post","link":"https:\/\/helloproject.es\/vigilancia\/safety-and-efficacy-of-a-feed-additive-consisting-of-l%e2%80%90lysine-sulfate-produced-with-corynebacterium-glutamicum-cgmcc-23982-for-all-animal-species-eppen-europa-sas-autoridad-europea-de-seguri\/","title":{"rendered":"Safety and efficacy of a feed additive consisting of l\u2010lysine sulfate produced with Corynebacterium glutamicum CGMCC 23982 for all animal species (Eppen Europa SAS) AUTORIDAD EUROPEA DE SEGURIDAD ALIMENTARIA: SUBVENCIONES\/NOTICIAS\/ADQUISCIONES"},"content":{"rendered":"<p>Following a request from the European Commission, the Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on l\u2010lysine sulfate produced by fermentation with a non\u2010genetically modified strain of Corynebacterium glutamicum (CGMCC 23982) when used as a nutritional additive in feed for all animal species. The active substance is l\u2010lysine. The FEEDAP Panel concluded that the production strain qualifies for the qualified presumption of safety (QPS) approach to safety assessment; therefore, l\u2010lysine sulfate produced with C. glutamicum CGMCC 23982 does not pose any safety concern associated with the production strain. l\u2010Lysine sulfate produced with C. glutamicum CGMCC 23982 is considered safe for the target species when administered via feed. When using l\u2010lysine sulfate, the background sulfur\/sulfate content in the compound feed should be taken into account when formulating diets. The FEEDAP Panel has concerns on the use of l\u2010lysine sulfate in water for drinking. l\u2010Lysine sulfate produced with C. glutamicum CGMCC 23982 is safe for the consumer and for the environment. With regard to user safety, the additive should be considered irritant to skin, eyes and the respiratory tract. Any exposure to the additive is a risk. l\u2010lysine sulfate is considered as an efficacious source of the essential amino acid l\u2010lysine for non\u2010ruminant animal species. For the supplemental l\u2010lysine to be as efficacious in ruminants as in non\u2010ruminant species, it would require protection against degradation in the rumen.<\/p>","protected":false},"excerpt":{"rendered":"<p>Following a request from the European Commission, the Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on l\u2010lysine sulfate produced by fermentation with a non\u2010genetically modified strain of Corynebacterium glutamicum (CGMCC 23982) when used as a nutritional additive in feed for all animal species. 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