{"id":114190,"date":"2025-05-05T15:30:31","date_gmt":"2025-05-05T14:30:31","guid":{"rendered":"https:\/\/helloproject.es\/vigilancia\/safety-assessment-of-the-substance-nn%e2%80%b2%e2%80%902%e2%80%904%e2%80%902%e2%80%90aminobenzamidobutylpentane%e2%80%9015%e2%80%90diylbis2%e2%80%90aminobenzamide-for-use-in-plastic-food-con\/"},"modified":"2025-05-05T15:30:31","modified_gmt":"2025-05-05T14:30:31","slug":"safety-assessment-of-the-substance-nn%e2%80%b2%e2%80%902%e2%80%904%e2%80%902%e2%80%90aminobenzamidobutylpentane%e2%80%9015%e2%80%90diylbis2%e2%80%90aminobenzamide-for-use-in-plastic-food-con","status":"publish","type":"post","link":"https:\/\/helloproject.es\/vigilancia\/safety-assessment-of-the-substance-nn%e2%80%b2%e2%80%902%e2%80%904%e2%80%902%e2%80%90aminobenzamidobutylpentane%e2%80%9015%e2%80%90diylbis2%e2%80%90aminobenzamide-for-use-in-plastic-food-con\/","title":{"rendered":"Safety assessment of the substance N,N\u2032\u2010(2\u2010(4\u2010(2\u2010aminobenzamido)butyl)pentane\u20101,5\u2010diyl)bis(2\u2010aminobenzamide) for use in plastic food contact materials AUTORIDAD EUROPEA DE SEGURIDAD ALIMENTARIA: SUBVENCIONES\/NOTICIAS\/ADQUISCIONES"},"content":{"rendered":"<p>The EFSA Panel on Food Contact Materials assessed the safety of N,N\u2032\u2010(2\u2010(4\u2010(2\u2010aminobenzamido)butyl)pentane\u20101,5\u2010diyl)bis(2\u2010aminobenzamide) to be used at up to 650 mg\/kg in polyethylene terephthalate (PET) to scavenge acetaldehyde (AA). Final articles are intended for contact with aqueous, acidic and low\u2010alcoholic beverages for long\u2010term storage at room temperature and below. The migration of the substance from PET bottles into 20% ethanol was 0.0038 mg\/kg food. The Panel calculated the potential migration of the summed reaction products not to exceed 0.02 mg\/kg food. From experimental studies, the Panel excluded genotoxicity concerns for the substance, for 2\u2010aminobenzamide +1 formaldehyde and 2\u2010aminobenzamide +1 AA, both with desaturation. In silico predictions, previous EFSA evaluations and the use of the threshold of toxicological concern (TTC) excluded genotoxicity concerns for 15 other impurities\/reaction products. A tentatively identified by\u2010product was predicted as possible DNA\u2010reactive<em> in vitro <\/em>mutagen and clastogen, due to its aromatic hydroxylamine group. Its modelled migration would not exceed 0.14 \u03bcg\/kg food, leading to a potential exposure below the TTC of 0.0025 \u03bcg\/kg body weight per day. Non\u2010identified reaction products are expected to be structurally related to the identified ones and, hence, not to raise concern for genotoxicity. The Panel concluded that the substance is not of safety concern for the consumer, if it is used as an additive at up to 650 mg\/kg in PET intended for contact with foods simulated by simulants A, B and C, for storage above 6 months at room temperature and below, including hot\u2010fill conditions and\/or heating up to 70\u00b0C\u2009\u2264\u2009T\u2009\u2264\u2009100\u00b0C for maximum t\u2009=\u2009120\/2<sup>((T\u221270)\/10)<\/sup> minutes. The substance should not be used for infant formula (including water used for reconstitution) and human milk. The migration of the substance should not exceed 0.05 mg\/kg food. The substance should not contain aromatic hydroxylamine derivatives at more than 0.15% w\/w.<\/p>","protected":false},"excerpt":{"rendered":"<p>The EFSA Panel on Food Contact Materials assessed the safety of N,N\u2032\u2010(2\u2010(4\u2010(2\u2010aminobenzamido)butyl)pentane\u20101,5\u2010diyl)bis(2\u2010aminobenzamide) to be used at up to 650 mg\/kg in polyethylene terephthalate (PET) to scavenge acetaldehyde (AA). Final articles are intended for contact with aqueous, acidic and low\u2010alcoholic beverages for long\u2010term storage at room temperature and below. The migration of the substance from PET [&hellip;]<\/p>\n","protected":false},"author":5,"featured_media":0,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[8,5,6],"tags":[],"class_list":["post-114190","post","type-post","status-publish","format-standard","hentry","category-ayudas-y-subvenciones","category-noticias","category-publicaciones"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v20.9 (Yoast SEO v27.7) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Safety assessment of the substance N,N\u2032\u2010(2\u2010(4\u2010(2\u2010aminobenzamido)butyl)pentane\u20101,5\u2010diyl)bis(2\u2010aminobenzamide) for use in plastic food contact materials AUTORIDAD EUROPEA DE SEGURIDAD ALIMENTARIA: SUBVENCIONES\/NOTICIAS\/ADQUISCIONES - bip4ex<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/helloproject.es\/vigilancia\/safety-assessment-of-the-substance-nn\u2032\u20102\u20104\u20102\u2010aminobenzamidobutylpentane\u201015\u2010diylbis2\u2010aminobenzamide-for-use-in-plastic-food-con\/\" \/>\n<meta property=\"og:locale\" content=\"es_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Safety assessment of the substance N,N\u2032\u2010(2\u2010(4\u2010(2\u2010aminobenzamido)butyl)pentane\u20101,5\u2010diyl)bis(2\u2010aminobenzamide) for use in plastic food contact materials AUTORIDAD EUROPEA DE SEGURIDAD ALIMENTARIA: SUBVENCIONES\/NOTICIAS\/ADQUISCIONES\" \/>\n<meta property=\"og:description\" content=\"The EFSA Panel on Food Contact Materials assessed the safety of N,N\u2032\u2010(2\u2010(4\u2010(2\u2010aminobenzamido)butyl)pentane\u20101,5\u2010diyl)bis(2\u2010aminobenzamide) to be used at up to 650 mg\/kg in polyethylene terephthalate (PET) to scavenge acetaldehyde (AA). 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