{"id":132137,"date":"2025-06-13T09:28:12","date_gmt":"2025-06-13T08:28:12","guid":{"rendered":"https:\/\/helloproject.es\/vigilancia\/asi-se-genera-el-ala-que-permite-a-las-moscas-mantener-el-equilibrio-en-el-aire\/"},"modified":"2025-06-13T09:28:12","modified_gmt":"2025-06-13T08:28:12","slug":"asi-se-genera-el-ala-que-permite-a-las-moscas-mantener-el-equilibrio-en-el-aire","status":"publish","type":"post","link":"https:\/\/helloproject.es\/vigilancia\/asi-se-genera-el-ala-que-permite-a-las-moscas-mantener-el-equilibrio-en-el-aire\/","title":{"rendered":"As\u00ed se genera el ala que permite a las moscas mantener el equilibrio en el aire"},"content":{"rendered":"

Un equipo del Instituto de Neurociencias (IN), centro mixto del Consejo Superior de Investigaciones Cient\u00edficas (CSIC) y la Universidad Miguel Hern\u00e1ndez (UMH) de Elche, ha desvelado c\u00f3mo se forma el halterio, una estructura fundamental para el vuelo de las moscas.<\/p>\n

Este peque\u00f1o \u00f3rgano, situado detr\u00e1s de las alas principales, act\u00faa como un giroscopio biol\u00f3gico, que ayuda al insecto a estabilizarse en el aire. El estudio ha sido publicado en la revista\u00a0Current Biology<\/a>.<\/p>\n

La investigaci\u00f3n ha sido liderada por\u00a0Jos\u00e9 Carlos Pastor Pareja, director del Laboratorio de Arquitectura Celular y Tisular en el Sistema Nervioso del Instituto de Neurociencias, y ha demostrado que, al contrario de lo que se pensaba, el halterio no es una estructura hueca, sino que sus dos superficies est\u00e1n conectadas internamente a trav\u00e9s de un sofisticado sistema celular que estabiliza su forma redondeada.<\/p>\n

<\/p>\n

Esta estructura es un sistema de estabilizaci\u00f3n que recuerda a los soportes arquitect\u00f3nicos: sin estas conexiones internas, el halterio se alarga y pierde su forma<\/p>\n

Jos\u00e9 Carlos Pastor Pareja, director del Laboratorio de Arquitectura Celular y Tisular en el Sistema Nervioso del Instituto de Neurociencias
\n<\/p>\n

Seg\u00fan explica Pastor Pareja, \u201cesta estructura es un sistema de estabilizaci\u00f3n que recuerda a los soportes arquitect\u00f3nicos: sin estas conexiones internas, el halterio se alarga y pierde su forma, igual que una carpa sin tensores\u201d.<\/p>\n

Durante el proceso que se conoce como metamorfosis de la mosca, el paso de larva a adulto, las alas y los halterios se desarrollan a partir de una fina capa de c\u00e9lulas.<\/p>\n

En el caso del halterio, el equipo ha descubierto que primero se degrada una matriz extracelular rica en col\u00e1geno que separa sus dos caras. Esta degradaci\u00f3n permite que se formen proyecciones celulares que conectan ambas superficies a trav\u00e9s de una matriz con otra prote\u00edna, la laminina, formando una especie de armaz\u00f3n interno.<\/p>\n

Estas conexiones act\u00faan como tensores biol\u00f3gicos, que permiten resistir las fuerzas que de otro modo deformar\u00edan el \u00f3rgano. Cuando este sistema falla, como ocurre en los modelos de mosca de la fruta (Drosophila melanogaster) modificados gen\u00e9ticamente por el equipo, el halterio pierde su forma redondeada, clave para su funci\u00f3n.<\/p>\n

El halterio est\u00e1 sometido a una tensi\u00f3n constante: una fuerza que tira de su base y otra que lo ancla a la cut\u00edcula externa del insecto<\/p>\n

Adem\u00e1s, el estudio revela que el halterio est\u00e1 sometido a una tensi\u00f3n constante: una fuerza que tira de su base y otra que lo ancla a la cut\u00edcula externa del insecto. Es precisamente este sistema interno de tensores el que equilibra ambas fuerzas para mantener su geometr\u00eda.<\/p>\n

.<\/p>\n

<\/a><\/p>\n

Microscop\u00eda electr\u00f3nica y grabaciones<\/h2>\n

Para observar estos efectos, el equipo utiliz\u00f3 t\u00e9cnicas avanzadas de microscop\u00eda electr\u00f3nica y grabaciones en vivo durante la metamorfosis de la mosca. \u201cHemos visto que se producen una serie de proyecciones celulares que estabilizan la forma redondeada del halterio al contrarrestar fuerzas que de otro modo lo deformar\u00edan\u201d, indica Pastor Pareja. Y a\u00f1ade el investigador, \u201ccuando eliminamos esta estructura de soporte en modelos mutantes, el \u00f3rgano pierde su geometr\u00eda funcional\u201d.<\/p>\n

El uso de modelos mutantes y el an\u00e1lisis de la matriz extracelular han sido claves para desentra\u00f1ar este mecanismo, que combina degradaci\u00f3n de col\u00e1geno, adhesi\u00f3n celular y tensores internos que refuerzan la estructura desde dentro.<\/p>\n

El uso de modelos mutantes y el an\u00e1lisis de la matriz extracelular han sido claves para desentra\u00f1ar este mecanismo<\/p>\n

Los resultados de este trabajo van m\u00e1s all\u00e1 del caso particular de la mosca de la fruta, ya que aportan ideas generales sobre c\u00f3mo los \u00f3rganos adquieren su forma en los animales, una cuesti\u00f3n fundamental en biolog\u00eda del desarrollo. Adem\u00e1s, pueden inspirar nuevas formas de abordar cuestiones como la ingenier\u00eda de tejidos o el dise\u00f1o de estructuras biomim\u00e9ticas.<\/p>\n

El estudio se ha llevado a cabo en colaboraci\u00f3n con los cient\u00edficos\u00a0Yuzhao Song\u00a0y\u00a0Tianhui Sun, de la Universidad de Tsinghua (China); los investigadores\u00a0Paloma Mart\u00edn\u00a0y\u00a0Ernesto S\u00e1nchez Herrero, del Centro de Biolog\u00eda Molecular Severo Ochoa (CBMSO, CSIC-UAM); y\u00a0Jorge Fern\u00e1ndez Herrero, de la Universidad de Alicante.<\/p>\n

Adem\u00e1s, ha contado con la financiaci\u00f3n del Ministerio de Ciencia, Innovaci\u00f3n y Universidades, el Programa para Centros de Excelencia Severo Ochoa del Instituto de Neurociencias (CSIC-UMH), la Fundaci\u00f3n Ram\u00f3n Areces y la Fundaci\u00f3n Nacional de Ciencia de China.\u00a0<\/p>\n

Referencia:<\/p>\n

Pastor-Pareja, J.C. \u00a0Mechanical coupling between dorsal and ventral surfaces shapes the Drosophila haltere. Current Biology<\/a>.\u00a0<\/p>","protected":false},"excerpt":{"rendered":"

Un equipo del Instituto de Neurociencias (IN), centro mixto del Consejo Superior de Investigaciones Cient\u00edficas (CSIC) y la Universidad Miguel Hern\u00e1ndez (UMH) de Elche, ha desvelado c\u00f3mo se forma el halterio, una estructura fundamental para el vuelo de las moscas. Este peque\u00f1o \u00f3rgano, situado detr\u00e1s de las alas principales, act\u00faa como un giroscopio biol\u00f3gico, que […]<\/p>\n","protected":false},"author":5,"featured_media":0,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[5],"tags":[],"class_list":["post-132137","post","type-post","status-publish","format-standard","hentry","category-noticias"],"yoast_head":"\nAs\u00ed se genera el ala que permite a las moscas mantener el equilibrio en el aire - bip4ex<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/helloproject.es\/vigilancia\/asi-se-genera-el-ala-que-permite-a-las-moscas-mantener-el-equilibrio-en-el-aire\/\" \/>\n<meta property=\"og:locale\" content=\"es_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"As\u00ed se genera el ala que permite a las moscas mantener el equilibrio en el aire\" \/>\n<meta property=\"og:description\" content=\"Un equipo del Instituto de Neurociencias (IN), centro mixto del Consejo Superior de Investigaciones Cient\u00edficas (CSIC) y la Universidad Miguel Hern\u00e1ndez (UMH) de Elche, ha desvelado c\u00f3mo se forma el halterio, una estructura fundamental para el vuelo de las moscas. 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