Agencia Europea de Medicamentos (EMA)<\/a> ha revisado la evidencia cient\u00edfica disponible sobre el riesgo de neutropenia y agranulocitosis asociado al tratamiento con clozapina y ha concluido que se reduzca la frecuencia de los controles hematol\u00f3gicos en los pacientes tratados con este antipsic\u00f3tico. Las nuevas evidencias cient\u00edficas sugieren que, aunque la neutropenia inducida por clozapina puede ocurrir en cualquier momento del tratamiento, su aparici\u00f3n es m\u00e1s frecuente durante el primer a\u00f1o, con una incidencia m\u00e1xima en las primeras 18 semanas de tratamiento. Posteriormente, la incidencia disminuye, reduci\u00e9ndose progresivamente tras dos a\u00f1os de tratamiento en pacientes sin episodios previos de neutropenia.<\/p>","protected":false},"excerpt":{"rendered":"El Comit\u00e9 para la Evaluaci\u00f3n de Riesgos en Farmacovigilancia (PRAC, por sus siglas en ingl\u00e9s) de la Agencia Europea de Medicamentos (EMA) ha revisado la evidencia cient\u00edfica disponible sobre el riesgo de neutropenia y agranulocitosis asociado al tratamiento con clozapina y ha concluido que se reduzca la frecuencia de los controles hematol\u00f3gicos en los pacientes […]<\/p>\n","protected":false},"author":5,"featured_media":0,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[5],"tags":[],"class_list":["post-154159","post","type-post","status-publish","format-standard","hentry","category-noticias"],"yoast_head":"\n
La AEMPS actualiza las recomendaciones de los controles hematol\u00f3gicos con clozapina - bip4ex<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/helloproject.es\/vigilancia\/la-aemps-actualiza-las-recomendaciones-de-los-controles-hematologicos-con-clozapina\/\" \/>\n<meta property=\"og:locale\" content=\"es_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"La AEMPS actualiza las recomendaciones de los controles hematol\u00f3gicos con clozapina\" \/>\n<meta property=\"og:description\" content=\"El Comit\u00e9 para la Evaluaci\u00f3n de Riesgos en Farmacovigilancia (PRAC, por sus siglas en ingl\u00e9s) de la Agencia Europea de Medicamentos (EMA) ha revisado la evidencia cient\u00edfica disponible sobre el riesgo de neutropenia y agranulocitosis asociado al tratamiento con clozapina y ha concluido que se reduzca la frecuencia de los controles hematol\u00f3gicos en los pacientes […]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/helloproject.es\/vigilancia\/la-aemps-actualiza-las-recomendaciones-de-los-controles-hematologicos-con-clozapina\/\" \/>\n<meta property=\"og:site_name\" content=\"bip4ex\" \/>\n<meta property=\"article:published_time\" content=\"2025-07-15T11:17:23+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.infosalut.com\/images\/noticies\/cc\/cc-epr326.jpg\" \/>\n<meta name=\"author\" content=\"Luis Miguel Mej\u00edas Ramos\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Escrito por\" \/>\n\t<meta name=\"twitter:data1\" content=\"Luis Miguel Mej\u00edas Ramos\" \/>\n\t<meta name=\"twitter:label2\" content=\"Tiempo de lectura\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minuto\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/helloproject.es\\\/vigilancia\\\/la-aemps-actualiza-las-recomendaciones-de-los-controles-hematologicos-con-clozapina\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/helloproject.es\\\/vigilancia\\\/la-aemps-actualiza-las-recomendaciones-de-los-controles-hematologicos-con-clozapina\\\/\"},\"author\":{\"name\":\"Luis Miguel Mej\u00edas Ramos\",\"@id\":\"https:\\\/\\\/helloproject.es\\\/vigilancia\\\/#\\\/schema\\\/person\\\/3767b0619d59a11570372c821f8619ca\"},\"headline\":\"La AEMPS actualiza las recomendaciones de los controles hematol\u00f3gicos con clozapina\",\"datePublished\":\"2025-07-15T11:17:23+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/helloproject.es\\\/vigilancia\\\/la-aemps-actualiza-las-recomendaciones-de-los-controles-hematologicos-con-clozapina\\\/\"},\"wordCount\":139,\"publisher\":{\"@id\":\"https:\\\/\\\/helloproject.es\\\/vigilancia\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/helloproject.es\\\/vigilancia\\\/la-aemps-actualiza-las-recomendaciones-de-los-controles-hematologicos-con-clozapina\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.infosalut.com\\\/images\\\/noticies\\\/cc\\\/cc-epr326.jpg\",\"articleSection\":[\"Noticias\"],\"inLanguage\":\"es\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/helloproject.es\\\/vigilancia\\\/la-aemps-actualiza-las-recomendaciones-de-los-controles-hematologicos-con-clozapina\\\/\",\"url\":\"https:\\\/\\\/helloproject.es\\\/vigilancia\\\/la-aemps-actualiza-las-recomendaciones-de-los-controles-hematologicos-con-clozapina\\\/\",\"name\":\"La AEMPS actualiza las recomendaciones de los controles hematol\u00f3gicos con clozapina - 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<\/p>\n