{"id":163641,"date":"2025-07-28T10:29:57","date_gmt":"2025-07-28T09:29:57","guid":{"rendered":"https:\/\/helloproject.es\/vigilancia\/guidance-on-the-use-of-read%e2%80%90across-for-chemical-safety-assessment-in-food-and-feed-autoridad-europea-de-seguridad-alimentaria-subvenciones-noticias-adquisciones\/"},"modified":"2025-07-28T10:29:57","modified_gmt":"2025-07-28T09:29:57","slug":"guidance-on-the-use-of-read%e2%80%90across-for-chemical-safety-assessment-in-food-and-feed-autoridad-europea-de-seguridad-alimentaria-subvenciones-noticias-adquisciones","status":"publish","type":"post","link":"https:\/\/helloproject.es\/vigilancia\/guidance-on-the-use-of-read%e2%80%90across-for-chemical-safety-assessment-in-food-and-feed-autoridad-europea-de-seguridad-alimentaria-subvenciones-noticias-adquisciones\/","title":{"rendered":"Guidance on the use of read\u2010across for chemical safety assessment in food and feed AUTORIDAD EUROPEA DE SEGURIDAD ALIMENTARIA: SUBVENCIONES\/NOTICIAS\/ADQUISCIONES"},"content":{"rendered":"<p>Read\u2010across is a method used in chemical risk assessment to predict the toxicological properties of a target substance by using data from structurally and mechanistically similar substances, known as source substances. EFSA&#8217;s Scientific Committee has developed an approach for using read\u2010across in food and feed risk assessment. This method provides a step\u2010by\u2010step guide to applying read\u2010across as part of a weight\u2010of\u2010evidence evaluation for individual substances. It includes an explanation of the key aspects to consider at each step of the read\u2010across workflow, i.e. problem formulation, target substance characterisation, source substance identification, source substance evaluation, data gap filling, uncertainty assessment, conclusion and reporting. It highlights the importance of clarity, impartiality and quality to derive transparent and reliable read\u2010across conclusions. A particular emphasis is placed on the analysis of uncertainty and whether the overall uncertainty can be lowered to tolerable levels by using standardised approaches, and\/or additional data from new approach methodologies (NAMs). The guidance outlines methods to integrate data from NAMs to support read\u2010across in the relevant steps, improving the robustness of the assessment. The ultimate goal is to equip risk assessors and applicants with a comprehensive framework to carry out read\u2010across assessments systematically and transparently, thereby supporting the safety evaluation of chemicals in the food and feed chain.<\/p>\n<p>This publication is linked to the technical report \u00abPublic consultation on the draft guidance on the use of read\u2010across for chemical safety assessment in food and feed\u00bb: <a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/10.2903\/sp.efsa.2025.EN-9569\">https:\/\/onlinelibrary.wiley.com\/doi\/10.2903\/sp.efsa.2025.EN-9569<\/a><\/p>\n<p>This publication is linked to the event report \u00abWorkshop on read\u2010across: role and guidance in chemical risk assessment\u00bb: <a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/10.2903\/sp.efsa.2025.EN-9521\">https:\/\/onlinelibrary.wiley.com\/doi\/10.2903\/sp.efsa.2025.EN-9521<\/a><\/p>\n<p>This publication is linked to the external scientific report \u00abRead\u2010Across Application for Food or Feed Ingredients\u00bb: <a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/10.2903\/sp.efsa.2024.EN-8811\">https:\/\/onlinelibrary.wiley.com\/doi\/10.2903\/sp.efsa.2024.EN-8811<\/a><\/p>","protected":false},"excerpt":{"rendered":"<p>Read\u2010across is a method used in chemical risk assessment to predict the toxicological properties of a target substance by using data from structurally and mechanistically similar substances, known as source substances. EFSA&#8217;s Scientific Committee has developed an approach for using read\u2010across in food and feed risk assessment. This method provides a step\u2010by\u2010step guide to applying [&hellip;]<\/p>\n","protected":false},"author":5,"featured_media":0,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[8,5,6],"tags":[],"class_list":["post-163641","post","type-post","status-publish","format-standard","hentry","category-ayudas-y-subvenciones","category-noticias","category-publicaciones"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v20.9 (Yoast SEO v27.5) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Guidance on the use of read\u2010across for chemical safety assessment in food and feed AUTORIDAD EUROPEA DE SEGURIDAD ALIMENTARIA: SUBVENCIONES\/NOTICIAS\/ADQUISCIONES - bip4ex<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/helloproject.es\/vigilancia\/guidance-on-the-use-of-read\u2010across-for-chemical-safety-assessment-in-food-and-feed-autoridad-europea-de-seguridad-alimentaria-subvenciones-noticias-adquisciones\/\" \/>\n<meta property=\"og:locale\" content=\"es_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Guidance on the use of read\u2010across for chemical safety assessment in food and feed AUTORIDAD EUROPEA DE SEGURIDAD ALIMENTARIA: SUBVENCIONES\/NOTICIAS\/ADQUISCIONES\" \/>\n<meta property=\"og:description\" content=\"Read\u2010across is a method used in chemical risk assessment to predict the toxicological properties of a target substance by using data from structurally and mechanistically similar substances, known as source substances. 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