{"id":178457,"date":"2025-08-20T13:29:50","date_gmt":"2025-08-20T12:29:50","guid":{"rendered":"https:\/\/helloproject.es\/vigilancia\/safety-of-lacto%e2%80%90n%e2%80%90tetraose-lnt-produced-by-a-derivative-strain-escherichia-coli-k%e2%80%9012-mg1655-inb_lnt_01-of-e-coli-k%e2%80%9012-mg1655-atcc-700926-as-a-novel-food-pursuant\/"},"modified":"2025-08-20T13:29:50","modified_gmt":"2025-08-20T12:29:50","slug":"safety-of-lacto%e2%80%90n%e2%80%90tetraose-lnt-produced-by-a-derivative-strain-escherichia-coli-k%e2%80%9012-mg1655-inb_lnt_01-of-e-coli-k%e2%80%9012-mg1655-atcc-700926-as-a-novel-food-pursuant","status":"publish","type":"post","link":"https:\/\/helloproject.es\/vigilancia\/safety-of-lacto%e2%80%90n%e2%80%90tetraose-lnt-produced-by-a-derivative-strain-escherichia-coli-k%e2%80%9012-mg1655-inb_lnt_01-of-e-coli-k%e2%80%9012-mg1655-atcc-700926-as-a-novel-food-pursuant\/","title":{"rendered":"Safety of lacto\u2010N\u2010tetraose (LNT) produced by a derivative strain (Escherichia coli K\u201012 MG1655 INB_LNT_01) of E. coli K\u201012 MG1655 (ATCC 700926) as a novel food pursuant to Regulation (EU) 2015\/2283 AUTORIDAD EUROPEA DE SEGURIDAD ALIMENTARIA: SUBVENCIONES\/NOTICIAS\/ADQUISCIONES"},"content":{"rendered":"<p>Following a request from the European Commission, the EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA) was asked to deliver an opinion on lacto\u2010N\u2010tetraose (LNT) as a novel food (NF) pursuant to Regulation (EU) 2015\/2283. The NF is mainly composed of the human\u2010identical milk oligosaccharide (HiMO) LNT, but it also contains lacto\u2010N\u2010triose II, d\u2010lactose, LNT\u2010fructose isomer and a small fraction of other related saccharides. The NF is produced by fermentation with a genetically modified strain (<em>Escherichia coli <\/em>K\u201012 MG1655 INB_LNT_01) of<em> E. coli <\/em>K\u201012 MG1655 (ATCC 700926). LNT when produced by fermentation with genetically modified strains of<em> E. coli <\/em>K\u201012 DH1 or<em> E. coli <\/em>BL21 is already authorised and included in the EU list of NFs. This application refers to a change in the production process and specifications, while the target population, conditions of use and consequently the anticipated intake remain unchanged. The information provided on the identity, production process, composition and specifications of the NF does not raise safety concerns. The intake of other carbohydrate\u2010type compounds structurally related to LNT is also considered of no safety concern. In line with other HiMOs, the safety assessment of this NF is mainly based on the comparison between the intake of breastfed infants and the estimated intake of the NF. Given that the NF would be consumed to the same extent as the already authorised LNT, the Panel considers that the consumption of the NF at the proposed uses and use levels does not raise safety concerns. The Panel concludes that the NF is safe under the proposed conditions of use.<\/p>","protected":false},"excerpt":{"rendered":"<p>Following a request from the European Commission, the EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA) was asked to deliver an opinion on lacto\u2010N\u2010tetraose (LNT) as a novel food (NF) pursuant to Regulation (EU) 2015\/2283. The NF is mainly composed of the human\u2010identical milk oligosaccharide (HiMO) LNT, but it also contains lacto\u2010N\u2010triose II, [&hellip;]<\/p>\n","protected":false},"author":5,"featured_media":0,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[8,5,6],"tags":[],"class_list":["post-178457","post","type-post","status-publish","format-standard","hentry","category-ayudas-y-subvenciones","category-noticias","category-publicaciones"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v20.9 (Yoast SEO v27.3) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Safety of lacto\u2010N\u2010tetraose (LNT) produced by a derivative strain (Escherichia coli K\u201012 MG1655 INB_LNT_01) of E. coli K\u201012 MG1655 (ATCC 700926) as a novel food pursuant to Regulation (EU) 2015\/2283 AUTORIDAD EUROPEA DE SEGURIDAD ALIMENTARIA: SUBVENCIONES\/NOTICIAS\/ADQUISCIONES - bip4ex<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/helloproject.es\/vigilancia\/safety-of-lacto\u2010n\u2010tetraose-lnt-produced-by-a-derivative-strain-escherichia-coli-k\u201012-mg1655-inb_lnt_01-of-e-coli-k\u201012-mg1655-atcc-700926-as-a-novel-food-pursuant\/\" \/>\n<meta property=\"og:locale\" content=\"es_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Safety of lacto\u2010N\u2010tetraose (LNT) produced by a derivative strain (Escherichia coli K\u201012 MG1655 INB_LNT_01) of E. coli K\u201012 MG1655 (ATCC 700926) as a novel food pursuant to Regulation (EU) 2015\/2283 AUTORIDAD EUROPEA DE SEGURIDAD ALIMENTARIA: SUBVENCIONES\/NOTICIAS\/ADQUISCIONES\" \/>\n<meta property=\"og:description\" content=\"Following a request from the European Commission, the EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA) was asked to deliver an opinion on lacto\u2010N\u2010tetraose (LNT) as a novel food (NF) pursuant to Regulation (EU) 2015\/2283. 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