{"id":182264,"date":"2025-09-23T13:28:19","date_gmt":"2025-09-23T12:28:19","guid":{"rendered":"https:\/\/helloproject.es\/vigilancia\/revelan-como-el-cerebro-organiza-y-dirige-su-actividad-mas-lenta\/"},"modified":"2025-09-23T13:28:19","modified_gmt":"2025-09-23T12:28:19","slug":"revelan-como-el-cerebro-organiza-y-dirige-su-actividad-mas-lenta","status":"publish","type":"post","link":"https:\/\/helloproject.es\/vigilancia\/revelan-como-el-cerebro-organiza-y-dirige-su-actividad-mas-lenta\/","title":{"rendered":"Revelan c\u00f3mo el cerebro organiza y dirige su actividad m\u00e1s lenta"},"content":{"rendered":"

Investigadores del\u00a0Instituto de Neurociencias, centro mixto del CSIC y de la Universidad Miguel Hern\u00e1ndez (UMH) de Elche,\u00a0han liderado un estudio que demuestra que la direccionalidad de las ondas lentas de la corteza cerebral depende de la excitabilidad de las neuronas y no \u00fanicamente de la estructura anat\u00f3mica.<\/p>\n

Los resultados de este trabajo, publicados en\u00a0iScience,\u00a0podr\u00edan ayudar a comprender mejor algunos estados como el sue\u00f1o profundo, la anestesia o patolog\u00edas como la epilepsia.<\/p>\n

Los resultados podr\u00edan ayudar a comprender mejor algunos estados como el sue\u00f1o profundo, la anestesia o patolog\u00edas como la epilepsia<\/p>\n

El cerebro nunca descansa. Incluso durante el sue\u00f1o profundo o bajo anestesia, mantiene una actividad el\u00e9ctrica r\u00edtmica conocida como oscilaciones lentas, se\u00f1alan los autores.\u00a0<\/p>\n

El hallazgo fue posible gracias a un modelo computacional avanzado que integra dos niveles de an\u00e1lisis: la actividad local de redes neuronales aisladas y la interacci\u00f3n global entre distintas \u00e1reas cerebrales. \u201cHasta ahora, la mayor\u00eda de los estudios trabajaban esas dos escalas por separado. La novedad de nuestro enfoque es que las analizamos conjuntamente, y eso nos ha permitido ver c\u00f3mo las diferencias locales se diluyen cuando las redes est\u00e1n conectadas\u201d, explica\u00a0Ram\u00f3n Reig\u00a0Reig, que ha coliderado el estudio junto al investigador Javier Alegre Cort\u00e9s.<\/p>\n

<\/a><\/p>\n

\u2018L\u00edder\u2019 neuronal<\/h2>\n

El modelo desarrollado por el equipo permiti\u00f3 observar que, cuando distintas regiones del cerebro se conectan, tienden a sincronizarse siguiendo el ritmo de la zona m\u00e1s activa. Esta regi\u00f3n act\u00faa como un \u201cl\u00edder\u201d neuronal que marca la direcci\u00f3n de las ondas lentas, independientemente de las diferencias anat\u00f3micas entre \u00e1reas.<\/p>\n

Los experimentos confirmaron que la direcci\u00f3n de estas oscilaciones depende del grado de excitabilidad de las neuronas. Al aumentar artificialmente esa excitabilidad en una zona concreta del cerebro de ratones anestesiados, las ondas cambiaron de direcci\u00f3n, lo que demuestra que no es la estructura, sino la din\u00e1mica neuronal, la que gu\u00eda su propagaci\u00f3n.<\/p>\n

Estas oscilaciones son clave para organizar la actividad cerebral durante el sue\u00f1o profundo o la anestesia<\/p>\n

Estas oscilaciones son clave para organizar la actividad cerebral durante el sue\u00f1o profundo o la anestesia. Cuando se alteran, pueden aparecer en momentos inapropiados o asociarse a trastornos como la epilepsia. El modelo tambi\u00e9n permiti\u00f3 simular distintos estados cerebrales y analizar qu\u00e9 factores influyen en la propagaci\u00f3n de las ondas, tanto a nivel local como global.<\/p>\n

Adem\u00e1s, el estudio representa un\u00a0avance metodol\u00f3gico. El modelo se basa en datos reales del cerebro de mam\u00edferos y permite explorar hip\u00f3tesis dif\u00edciles de comprobar en laboratorio, lo que refuerza su valor como herramienta complementaria a los experimentos.<\/p>","protected":false},"excerpt":{"rendered":"

Investigadores del\u00a0Instituto de Neurociencias, centro mixto del CSIC y de la Universidad Miguel Hern\u00e1ndez (UMH) de Elche,\u00a0han liderado un estudio que demuestra que la direccionalidad de las ondas lentas de la corteza cerebral depende de la excitabilidad de las neuronas y no \u00fanicamente de la estructura anat\u00f3mica. Los resultados de este trabajo, publicados en\u00a0iScience,\u00a0podr\u00edan ayudar […]<\/p>\n","protected":false},"author":5,"featured_media":0,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[5],"tags":[],"class_list":["post-182264","post","type-post","status-publish","format-standard","hentry","category-noticias"],"yoast_head":"\nRevelan c\u00f3mo el cerebro organiza y dirige su actividad m\u00e1s lenta - bip4ex<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/helloproject.es\/vigilancia\/revelan-como-el-cerebro-organiza-y-dirige-su-actividad-mas-lenta\/\" \/>\n<meta property=\"og:locale\" content=\"es_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Revelan c\u00f3mo el cerebro organiza y dirige su actividad m\u00e1s lenta\" \/>\n<meta property=\"og:description\" content=\"Investigadores del\u00a0Instituto de Neurociencias, centro mixto del CSIC y de la Universidad Miguel Hern\u00e1ndez (UMH) de Elche,\u00a0han liderado un estudio que demuestra que la direccionalidad de las ondas lentas de la corteza cerebral depende de la excitabilidad de las neuronas y no \u00fanicamente de la estructura anat\u00f3mica. 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