{"id":183547,"date":"2025-10-07T07:28:25","date_gmt":"2025-10-07T06:28:25","guid":{"rendered":"https:\/\/helloproject.es\/vigilancia\/consiguen-revertir-el-alzheimer-en-ratones-con-el-uso-de-nanoparticulas\/"},"modified":"2025-10-07T07:28:25","modified_gmt":"2025-10-07T06:28:25","slug":"consiguen-revertir-el-alzheimer-en-ratones-con-el-uso-de-nanoparticulas","status":"publish","type":"post","link":"https:\/\/helloproject.es\/vigilancia\/consiguen-revertir-el-alzheimer-en-ratones-con-el-uso-de-nanoparticulas\/","title":{"rendered":"Consiguen revertir el alzh\u00e9imer en ratones con el uso de nanopart\u00edculas"},"content":{"rendered":"

Un equipo internacional codirigido por el Instituto de Bioingenier\u00eda de Catalu\u00f1a (IBEC) y el Hospital West China de la Universidad de Sichuan (WCHSU), con participaci\u00f3n de investigadores del Reino Unido, ha demostrado una estrategia de nanotecnolog\u00eda que revierte la enfermedad de Alzheimer en ratones.<\/p>\n

A diferencia de la nanomedicina habitual, que emplea nanopart\u00edculas como veh\u00edculos de f\u00e1rmacos, este m\u00e9todo utiliza part\u00edculas bioactivas por s\u00ed mismas, denominadas f\u00e1rmacos supramoleculares. En lugar de dirigirse a las neuronas, el tratamiento act\u00faa sobre la barrera hematoencef\u00e1lica (BBB), la interfaz que regula el entorno del cerebro.<\/p>\n

En lugar de emplear nanopart\u00edculas como veh\u00edculos de f\u00e1rmacos, este m\u00e9todo utiliza part\u00edculas bioactivas por s\u00ed mismas<\/p>\n

Al reparar esta barrera, que funciona como guardi\u00e1n frente a toxinas y pat\u00f3genos, los cient\u00edficos lograron restaurar el equilibrio del sistema vascular cerebral y revertir la patolog\u00eda en modelos animales.<\/p>\n

El cerebro consume un 20 % de la energ\u00eda en adultos y hasta un 60 % en ni\u00f1os, a trav\u00e9s de un denso entramado de capilares. Cuando la barrera hematoencef\u00e1lica se ve comprometida, el sistema de limpieza cerebral deja de funcionar correctamente, lo que favorece la acumulaci\u00f3n de la prote\u00edna beta amiloide (A\u03b2), una de las principales caracter\u00edsticas del alzh\u00e9imer.<\/p>\n

<\/a><\/p>\n

Directas al torrente sangu\u00edneo<\/h2>\n

Los investigadores lograron que las nanopart\u00edculas permitieran el paso de estas prote\u00ednas de desecho al torrente sangu\u00edneo para su eliminaci\u00f3n. En modelos de rat\u00f3n programados gen\u00e9ticamente para producir grandes cantidades de A\u03b2 y desarrollar deterioro cognitivo, la administraci\u00f3n de solo tres dosis consigui\u00f3 resultados notables.<\/p>\n

En modelos de rat\u00f3n modificados para producir grandes cantidades de A\u03b2 y desarrollar deterioro cognitivo, la administraci\u00f3n de solo tres dosis consigui\u00f3 resultados notables<\/p>\n

\u201cSolo una hora despu\u00e9s de la inyecci\u00f3n observamos una reducci\u00f3n del 50-60 % en la cantidad de A\u03b2 dentro del cerebro\u201d, explica Junyang Chen, primer coautor del estudio e investigador del Hospital West China y del University College London.<\/p>\n

M\u00e1s all\u00e1 de la eliminaci\u00f3n inmediata de prote\u00ednas t\u00f3xicas, el equipo observ\u00f3 efectos terap\u00e9uticos\u00a0duraderos. En uno de los experimentos, un rat\u00f3n de 12 meses (equivalente a un humano de 60 a\u00f1os) recibi\u00f3 el tratamiento y fue analizado seis meses despu\u00e9s. A los 18 meses, edad comparable a los 90 a\u00f1os en humanos, el animal mostr\u00f3 un comportamiento similar al de un rat\u00f3n sano.<\/p>\n

Un rat\u00f3n tratado a los 12 meses recuper\u00f3, medio a\u00f1o despu\u00e9s, el comportamiento de un animal sano pese a tener una edad equivalente a 90 a\u00f1os en humanos<\/p>\n

\u201cEl efecto a largo plazo proviene de la restauraci\u00f3n del sistema vascular del cerebro. Creemos que funciona como una cascada: cuando la vascularizaci\u00f3n recupera su funci\u00f3n, empieza a eliminar A\u03b2 y otras mol\u00e9culas da\u00f1inas, lo que permite que el sistema vuelva a equilibrarse. Nuestras nanopart\u00edculas act\u00faan como un f\u00e1rmaco y parecen activar un mecanismo de retroalimentaci\u00f3n que normaliza esta v\u00eda de eliminaci\u00f3n\u201d, afirma Giuseppe Battaglia, profesor de investigaci\u00f3n ICREA en el IBEC y l\u00edder del estudio.<\/p>\n

<\/a><\/p>\n

F\u00e1rmacos supramoleculares<\/h2>\n

En condiciones normales, la prote\u00edna LRP1 transporta la beta amiloide a trav\u00e9s de la barrera hematoencef\u00e1lica para su eliminaci\u00f3n. Este proceso puede bloquearse si la prote\u00edna se une en exceso, o ser insuficiente si la se\u00f1al es demasiado d\u00e9bil, en ambos casos facilitando la acumulaci\u00f3n en el cerebro.<\/p>\n

Los f\u00e1rmacos supramoleculares desarrollados imitan a los ligandos de LRP1, favoreciendo el transporte de A\u03b2 y restableciendo el sistema natural de limpieza. As\u00ed, ayudan a restaurar el equilibrio vascular y la funci\u00f3n cerebral.<\/p>\n

<\/p>\n

Demostramos una eficacia significativa para una r\u00e1pida eliminaci\u00f3n de A\u03b2, restaurar la funci\u00f3n de la barrera hematoencef\u00e1lica y revertir la patolog\u00eda del Alzheime<\/p>\n

Lorena Ruiz P\u00e9rez, coautora del estudio (IBEC)
\n<\/p>\n

\u201cDemostramos una eficacia significativa para lograr una r\u00e1pida eliminaci\u00f3n de A\u03b2, restaurar la funci\u00f3n de la barrera hematoencef\u00e1lica y revertir la patolog\u00eda del Alzheimer\u201d, concluye\u00a0Lorena Ruiz P\u00e9rez, investigadora del grupo de Bi\u00f3nica Molecular del IBEC y profesora adjunta Serra Hunter en la Universidad de Barcelona.<\/p>\n

<\/a><\/p>\n

Ingenier\u00eda molecular\u00a0<\/h2>\n

El trabajo introduce una estrategia de ingenier\u00eda molecular que dise\u00f1a nanopart\u00edculas con control preciso de tama\u00f1o y ligandos superficiales, capaces de interactuar espec\u00edficamente con receptores celulares.<\/p>\n

Seg\u00fan los autores, este m\u00e9todo podr\u00eda abrir la v\u00eda\u00a0 a nuevas intervenciones cl\u00ednicas dirigidas a los mecanismos vasculares del alzh\u00e9imer<\/p>\n

Seg\u00fan los autores, este m\u00e9todo podr\u00eda abrir la v\u00eda\u00a0 a nuevas intervenciones cl\u00ednicas dirigidas a los mecanismos vasculares del alzh\u00e9imer.<\/p>\n

El estudio ha sido fruto de la colaboraci\u00f3n entre el IBEC, el Hospital West China y el Hospital Xiamen West China de la Universidad de Sichuan, el University College London, la Universidad de Barcelona, la Academia China de Ciencias M\u00e9dicas y la Instituci\u00f3n Catalana de Investigaci\u00f3n y Estudios Avanzados (ICREA).<\/p>\n

Referencia:<\/p>\n

Junyang Chen, Pan Xiang, Aroa Duro-Castano et al.\u00a0\u201cMultivalent modulation of endothelial LRP1 induces fast neurovascular amyloid-\u03b2 clearance and cognitive function improvement in Alzheimer\u2019s disease models\u201d.\u00a0Signal Transduction and Targeted Therapy, 2025.<\/p>","protected":false},"excerpt":{"rendered":"

Un equipo internacional codirigido por el Instituto de Bioingenier\u00eda de Catalu\u00f1a (IBEC) y el Hospital West China de la Universidad de Sichuan (WCHSU), con participaci\u00f3n de investigadores del Reino Unido, ha demostrado una estrategia de nanotecnolog\u00eda que revierte la enfermedad de Alzheimer en ratones. A diferencia de la nanomedicina habitual, que emplea nanopart\u00edculas como veh\u00edculos […]<\/p>\n","protected":false},"author":5,"featured_media":0,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[5],"tags":[],"class_list":["post-183547","post","type-post","status-publish","format-standard","hentry","category-noticias"],"yoast_head":"\nConsiguen revertir el alzh\u00e9imer en ratones con el uso de nanopart\u00edculas - bip4ex<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/helloproject.es\/vigilancia\/consiguen-revertir-el-alzheimer-en-ratones-con-el-uso-de-nanoparticulas\/\" \/>\n<meta property=\"og:locale\" content=\"es_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Consiguen revertir el alzh\u00e9imer en ratones con el uso de nanopart\u00edculas\" \/>\n<meta property=\"og:description\" content=\"Un equipo internacional codirigido por el Instituto de Bioingenier\u00eda de Catalu\u00f1a (IBEC) y el Hospital West China de la Universidad de Sichuan (WCHSU), con participaci\u00f3n de investigadores del Reino Unido, ha demostrado una estrategia de nanotecnolog\u00eda que revierte la enfermedad de Alzheimer en ratones. A diferencia de la nanomedicina habitual, que emplea nanopart\u00edculas como veh\u00edculos […]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/helloproject.es\/vigilancia\/consiguen-revertir-el-alzheimer-en-ratones-con-el-uso-de-nanoparticulas\/\" \/>\n<meta property=\"og:site_name\" content=\"bip4ex\" \/>\n<meta property=\"article:published_time\" content=\"2025-10-07T06:28:25+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.agenciasinc.es\/bundles\/app\/images\/quotebefore.png\" \/>\n<meta name=\"author\" content=\"Luis Miguel Mej\u00edas Ramos\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Escrito por\" \/>\n\t<meta name=\"twitter:data1\" content=\"Luis Miguel Mej\u00edas Ramos\" \/>\n\t<meta name=\"twitter:label2\" content=\"Tiempo de lectura\" \/>\n\t<meta name=\"twitter:data2\" content=\"4 minutos\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/helloproject.es\\\/vigilancia\\\/consiguen-revertir-el-alzheimer-en-ratones-con-el-uso-de-nanoparticulas\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/helloproject.es\\\/vigilancia\\\/consiguen-revertir-el-alzheimer-en-ratones-con-el-uso-de-nanoparticulas\\\/\"},\"author\":{\"name\":\"Luis Miguel Mej\u00edas Ramos\",\"@id\":\"https:\\\/\\\/helloproject.es\\\/vigilancia\\\/#\\\/schema\\\/person\\\/3767b0619d59a11570372c821f8619ca\"},\"headline\":\"Consiguen revertir el alzh\u00e9imer en ratones con el uso de nanopart\u00edculas\",\"datePublished\":\"2025-10-07T06:28:25+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/helloproject.es\\\/vigilancia\\\/consiguen-revertir-el-alzheimer-en-ratones-con-el-uso-de-nanoparticulas\\\/\"},\"wordCount\":905,\"publisher\":{\"@id\":\"https:\\\/\\\/helloproject.es\\\/vigilancia\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/helloproject.es\\\/vigilancia\\\/consiguen-revertir-el-alzheimer-en-ratones-con-el-uso-de-nanoparticulas\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.agenciasinc.es\\\/bundles\\\/app\\\/images\\\/quotebefore.png\",\"articleSection\":[\"Noticias\"],\"inLanguage\":\"es\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/helloproject.es\\\/vigilancia\\\/consiguen-revertir-el-alzheimer-en-ratones-con-el-uso-de-nanoparticulas\\\/\",\"url\":\"https:\\\/\\\/helloproject.es\\\/vigilancia\\\/consiguen-revertir-el-alzheimer-en-ratones-con-el-uso-de-nanoparticulas\\\/\",\"name\":\"Consiguen revertir el alzh\u00e9imer en ratones con el uso de nanopart\u00edculas - bip4ex\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/helloproject.es\\\/vigilancia\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/helloproject.es\\\/vigilancia\\\/consiguen-revertir-el-alzheimer-en-ratones-con-el-uso-de-nanoparticulas\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/helloproject.es\\\/vigilancia\\\/consiguen-revertir-el-alzheimer-en-ratones-con-el-uso-de-nanoparticulas\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.agenciasinc.es\\\/bundles\\\/app\\\/images\\\/quotebefore.png\",\"datePublished\":\"2025-10-07T06:28:25+00:00\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/helloproject.es\\\/vigilancia\\\/consiguen-revertir-el-alzheimer-en-ratones-con-el-uso-de-nanoparticulas\\\/#breadcrumb\"},\"inLanguage\":\"es\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/helloproject.es\\\/vigilancia\\\/consiguen-revertir-el-alzheimer-en-ratones-con-el-uso-de-nanoparticulas\\\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"es\",\"@id\":\"https:\\\/\\\/helloproject.es\\\/vigilancia\\\/consiguen-revertir-el-alzheimer-en-ratones-con-el-uso-de-nanoparticulas\\\/#primaryimage\",\"url\":\"https:\\\/\\\/www.agenciasinc.es\\\/bundles\\\/app\\\/images\\\/quotebefore.png\",\"contentUrl\":\"https:\\\/\\\/www.agenciasinc.es\\\/bundles\\\/app\\\/images\\\/quotebefore.png\"},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/helloproject.es\\\/vigilancia\\\/consiguen-revertir-el-alzheimer-en-ratones-con-el-uso-de-nanoparticulas\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/helloproject.es\\\/vigilancia\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Consiguen revertir el alzh\u00e9imer en ratones con el uso de nanopart\u00edculas\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/helloproject.es\\\/vigilancia\\\/#website\",\"url\":\"https:\\\/\\\/helloproject.es\\\/vigilancia\\\/\",\"name\":\"bip4ex\",\"description\":\"Vigilancia Tecnol\u00f3gica\",\"publisher\":{\"@id\":\"https:\\\/\\\/helloproject.es\\\/vigilancia\\\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/helloproject.es\\\/vigilancia\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"es\"},{\"@type\":\"Organization\",\"@id\":\"https:\\\/\\\/helloproject.es\\\/vigilancia\\\/#organization\",\"name\":\"Helloproject.es\",\"url\":\"https:\\\/\\\/helloproject.es\\\/vigilancia\\\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"es\",\"@id\":\"https:\\\/\\\/helloproject.es\\\/vigilancia\\\/#\\\/schema\\\/logo\\\/image\\\/\",\"url\":\"https:\\\/\\\/helloproject.es\\\/vigilancia\\\/wp-content\\\/uploads\\\/2023\\\/07\\\/bip4ex.png\",\"contentUrl\":\"https:\\\/\\\/helloproject.es\\\/vigilancia\\\/wp-content\\\/uploads\\\/2023\\\/07\\\/bip4ex.png\",\"width\":322,\"height\":365,\"caption\":\"Helloproject.es\"},\"image\":{\"@id\":\"https:\\\/\\\/helloproject.es\\\/vigilancia\\\/#\\\/schema\\\/logo\\\/image\\\/\"}},{\"@type\":\"Person\",\"@id\":\"https:\\\/\\\/helloproject.es\\\/vigilancia\\\/#\\\/schema\\\/person\\\/3767b0619d59a11570372c821f8619ca\",\"name\":\"Luis Miguel Mej\u00edas Ramos\",\"url\":\"https:\\\/\\\/helloproject.es\\\/vigilancia\\\/author\\\/luismi\\\/\"}]}<\/script>\n<!-- \/ Yoast SEO Premium plugin. -->","yoast_head_json":{"title":"Consiguen revertir el alzh\u00e9imer en ratones con el uso de nanopart\u00edculas - bip4ex","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/helloproject.es\/vigilancia\/consiguen-revertir-el-alzheimer-en-ratones-con-el-uso-de-nanoparticulas\/","og_locale":"es_ES","og_type":"article","og_title":"Consiguen revertir el alzh\u00e9imer en ratones con el uso de nanopart\u00edculas","og_description":"Un equipo internacional codirigido por el Instituto de Bioingenier\u00eda de Catalu\u00f1a (IBEC) y el Hospital West China de la Universidad de Sichuan (WCHSU), con participaci\u00f3n de investigadores del Reino Unido, ha demostrado una estrategia de nanotecnolog\u00eda que revierte la enfermedad de Alzheimer en ratones. A diferencia de la nanomedicina habitual, que emplea nanopart\u00edculas como veh\u00edculos […]","og_url":"https:\/\/helloproject.es\/vigilancia\/consiguen-revertir-el-alzheimer-en-ratones-con-el-uso-de-nanoparticulas\/","og_site_name":"bip4ex","article_published_time":"2025-10-07T06:28:25+00:00","og_image":[{"url":"https:\/\/www.agenciasinc.es\/bundles\/app\/images\/quotebefore.png","type":"","width":"","height":""}],"author":"Luis Miguel Mej\u00edas Ramos","twitter_card":"summary_large_image","twitter_misc":{"Escrito por":"Luis Miguel Mej\u00edas Ramos","Tiempo de lectura":"4 minutos"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/helloproject.es\/vigilancia\/consiguen-revertir-el-alzheimer-en-ratones-con-el-uso-de-nanoparticulas\/#article","isPartOf":{"@id":"https:\/\/helloproject.es\/vigilancia\/consiguen-revertir-el-alzheimer-en-ratones-con-el-uso-de-nanoparticulas\/"},"author":{"name":"Luis Miguel Mej\u00edas Ramos","@id":"https:\/\/helloproject.es\/vigilancia\/#\/schema\/person\/3767b0619d59a11570372c821f8619ca"},"headline":"Consiguen revertir el alzh\u00e9imer en ratones con el uso de nanopart\u00edculas","datePublished":"2025-10-07T06:28:25+00:00","mainEntityOfPage":{"@id":"https:\/\/helloproject.es\/vigilancia\/consiguen-revertir-el-alzheimer-en-ratones-con-el-uso-de-nanoparticulas\/"},"wordCount":905,"publisher":{"@id":"https:\/\/helloproject.es\/vigilancia\/#organization"},"image":{"@id":"https:\/\/helloproject.es\/vigilancia\/consiguen-revertir-el-alzheimer-en-ratones-con-el-uso-de-nanoparticulas\/#primaryimage"},"thumbnailUrl":"https:\/\/www.agenciasinc.es\/bundles\/app\/images\/quotebefore.png","articleSection":["Noticias"],"inLanguage":"es"},{"@type":"WebPage","@id":"https:\/\/helloproject.es\/vigilancia\/consiguen-revertir-el-alzheimer-en-ratones-con-el-uso-de-nanoparticulas\/","url":"https:\/\/helloproject.es\/vigilancia\/consiguen-revertir-el-alzheimer-en-ratones-con-el-uso-de-nanoparticulas\/","name":"Consiguen revertir el alzh\u00e9imer en ratones con el uso de nanopart\u00edculas - bip4ex","isPartOf":{"@id":"https:\/\/helloproject.es\/vigilancia\/#website"},"primaryImageOfPage":{"@id":"https:\/\/helloproject.es\/vigilancia\/consiguen-revertir-el-alzheimer-en-ratones-con-el-uso-de-nanoparticulas\/#primaryimage"},"image":{"@id":"https:\/\/helloproject.es\/vigilancia\/consiguen-revertir-el-alzheimer-en-ratones-con-el-uso-de-nanoparticulas\/#primaryimage"},"thumbnailUrl":"https:\/\/www.agenciasinc.es\/bundles\/app\/images\/quotebefore.png","datePublished":"2025-10-07T06:28:25+00:00","breadcrumb":{"@id":"https:\/\/helloproject.es\/vigilancia\/consiguen-revertir-el-alzheimer-en-ratones-con-el-uso-de-nanoparticulas\/#breadcrumb"},"inLanguage":"es","potentialAction":[{"@type":"ReadAction","target":["https:\/\/helloproject.es\/vigilancia\/consiguen-revertir-el-alzheimer-en-ratones-con-el-uso-de-nanoparticulas\/"]}]},{"@type":"ImageObject","inLanguage":"es","@id":"https:\/\/helloproject.es\/vigilancia\/consiguen-revertir-el-alzheimer-en-ratones-con-el-uso-de-nanoparticulas\/#primaryimage","url":"https:\/\/www.agenciasinc.es\/bundles\/app\/images\/quotebefore.png","contentUrl":"https:\/\/www.agenciasinc.es\/bundles\/app\/images\/quotebefore.png"},{"@type":"BreadcrumbList","@id":"https:\/\/helloproject.es\/vigilancia\/consiguen-revertir-el-alzheimer-en-ratones-con-el-uso-de-nanoparticulas\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/helloproject.es\/vigilancia\/"},{"@type":"ListItem","position":2,"name":"Consiguen revertir el alzh\u00e9imer en ratones con el uso de nanopart\u00edculas"}]},{"@type":"WebSite","@id":"https:\/\/helloproject.es\/vigilancia\/#website","url":"https:\/\/helloproject.es\/vigilancia\/","name":"bip4ex","description":"Vigilancia Tecnol\u00f3gica","publisher":{"@id":"https:\/\/helloproject.es\/vigilancia\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/helloproject.es\/vigilancia\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"es"},{"@type":"Organization","@id":"https:\/\/helloproject.es\/vigilancia\/#organization","name":"Helloproject.es","url":"https:\/\/helloproject.es\/vigilancia\/","logo":{"@type":"ImageObject","inLanguage":"es","@id":"https:\/\/helloproject.es\/vigilancia\/#\/schema\/logo\/image\/","url":"https:\/\/helloproject.es\/vigilancia\/wp-content\/uploads\/2023\/07\/bip4ex.png","contentUrl":"https:\/\/helloproject.es\/vigilancia\/wp-content\/uploads\/2023\/07\/bip4ex.png","width":322,"height":365,"caption":"Helloproject.es"},"image":{"@id":"https:\/\/helloproject.es\/vigilancia\/#\/schema\/logo\/image\/"}},{"@type":"Person","@id":"https:\/\/helloproject.es\/vigilancia\/#\/schema\/person\/3767b0619d59a11570372c821f8619ca","name":"Luis Miguel Mej\u00edas Ramos","url":"https:\/\/helloproject.es\/vigilancia\/author\/luismi\/"}]}},"_links":{"self":[{"href":"https:\/\/helloproject.es\/vigilancia\/wp-json\/wp\/v2\/posts\/183547","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/helloproject.es\/vigilancia\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/helloproject.es\/vigilancia\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/helloproject.es\/vigilancia\/wp-json\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/helloproject.es\/vigilancia\/wp-json\/wp\/v2\/comments?post=183547"}],"version-history":[{"count":0,"href":"https:\/\/helloproject.es\/vigilancia\/wp-json\/wp\/v2\/posts\/183547\/revisions"}],"wp:attachment":[{"href":"https:\/\/helloproject.es\/vigilancia\/wp-json\/wp\/v2\/media?parent=183547"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/helloproject.es\/vigilancia\/wp-json\/wp\/v2\/categories?post=183547"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/helloproject.es\/vigilancia\/wp-json\/wp\/v2\/tags?post=183547"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}