{"id":196709,"date":"2026-01-28T10:28:04","date_gmt":"2026-01-28T09:28:04","guid":{"rendered":"https:\/\/helloproject.es\/vigilancia\/las-bacterias-podrian-ser-el-andamio-sobre-el-que-se-forman-las-piedras-del-rinon\/"},"modified":"2026-01-28T10:28:04","modified_gmt":"2026-01-28T09:28:04","slug":"las-bacterias-podrian-ser-el-andamio-sobre-el-que-se-forman-las-piedras-del-rinon","status":"publish","type":"post","link":"https:\/\/helloproject.es\/vigilancia\/las-bacterias-podrian-ser-el-andamio-sobre-el-que-se-forman-las-piedras-del-rinon\/","title":{"rendered":"Las bacterias podr\u00edan ser el andamio sobre el que se forman las piedras del ri\u00f1\u00f3n"},"content":{"rendered":"

Hasta ahora, la ciencia m\u00e9dica asum\u00eda que la mayor\u00eda de los c\u00e1lculos renales se formaban mediante\u00a0procesos puramente qu\u00edmicos y f\u00edsicos: una acumulaci\u00f3n de cristales por saturaci\u00f3n de sustancias en la orina. Sin embargo, un estudio liderado por la Universidad de California en Los \u00c1ngeles (UCLA) y publicado esta semana<\/a> en la revista PNAS acaba de desmontar este paradigma al demostrar que incluso los c\u00e1lculos m\u00e1s comunes albergan bacterias vivas en su interior.<\/p>\n

Hasta ahora, la ciencia m\u00e9dica asum\u00eda que la mayor\u00eda de los c\u00e1lculos renales se formaban mediante\u00a0procesos puramente qu\u00edmicos y f\u00edsicos<\/p>\n

El equipo analiz\u00f3 mediante microscop\u00eda electr\u00f3nica y de fluorescencia piedras de oxalato c\u00e1lcico (CaOx), que representan casi el 80 % de los casos cl\u00ednicos. De forma inesperada, detectaron no solo la presencia de microorganismos, sino\u00a0capas estructuradas de bacterias \u2014conocidas como biofilms\u2014 integradas profundamente en la arquitectura de los cristales.<\/p>\n

\u201cEste avance desaf\u00eda la suposici\u00f3n de que estas piedras se desarrollan \u00fanicamente por procesos qu\u00edmicos\u201d, explica\u00a0Kymora Scotland, profesora de urolog\u00eda en la Escuela de Medicina David Geffen de la UCLA y coautora principal del estudio. \u201cDemuestra que las bacterias pueden residir dentro de los c\u00e1lculos y pueden contribuir activamente a su formaci\u00f3n\u201d.<\/p>\n


\n \"Crean
\n <\/a><\/p>\n

<\/a><\/p>\n

Crean tres atlas del ri\u00f1\u00f3n, el intestino y la placenta a resoluci\u00f3n unicelular<\/h3>\n

<\/p>\n


\n Adhik Arrilucea
\n <\/a> <\/p>\n

<\/a><\/p>\n

Una nueva v\u00eda contra las infecciones recurrentes<\/h2>\n

Este hallazgo podr\u00eda ser la pieza que faltaba para entender la estrecha relaci\u00f3n entre las infecciones del tracto urinario y la aparici\u00f3n recurrente de piedras en el ri\u00f1\u00f3n. Seg\u00fan los investigadores, las bacterias no ser\u00edan meras\u00a0\u2018pasajeras\u2019, sino agentes que facilitan la nucleaci\u00f3n de los cristales, sirviendo como andamiaje sobre el cual la piedra crece.<\/p>\n

Aproximadamente\u00a0una de cada once personas sufrir\u00e1 c\u00e1lculos renales\u00a0a lo largo de su vida, una prevalencia que ha ido en aumento\u00a0debido a factores como el s\u00edndrome metab\u00f3lico y la baja hidrataci\u00f3n<\/p>\n

La relevancia cl\u00ednica es inmediata: aproximadamente una de cada once personas sufrir\u00e1 c\u00e1lculos renales a lo largo de su vida, una prevalencia que ha ido en aumento debido a factores como el s\u00edndrome metab\u00f3lico y la baja hidrataci\u00f3n. \u201cAl descubrir este mecanismo, se abre la puerta a nuevas estrategias terap\u00e9uticas que se dirijan al entorno microbiano de los c\u00e1lculos para prevenir su reaparici\u00f3n\u201d, a\u00f1ade Scotland.<\/p>\n

El equipo multidisciplinar, que incluye a expertos en bioingenier\u00eda y qu\u00edmica, ya trabaja en determinar qu\u00e9 especies bacterianas espec\u00edficas poseen la capacidad de nuclear estas piedras y por qu\u00e9 ciertos pacientes son m\u00e1s susceptibles a este proceso. Aunque el estudio se centr\u00f3 en los c\u00e1lculos de calcio, los cient\u00edficos sospechan que este mecanismo microbiano podr\u00eda estar presente en otros tipos de c\u00e1lculos menos frecuentes.<\/p>\n

Referencia:<\/p>\n

Scotland, K. et al., \u201cIntercalated bacterial biofilms are intrinsic internal components of calcium-based kidney stones<\/a>\u201d,\u00a0Proceedings of the National Academy of Sciences, 2025.\u00a0<\/p>","protected":false},"excerpt":{"rendered":"

Hasta ahora, la ciencia m\u00e9dica asum\u00eda que la mayor\u00eda de los c\u00e1lculos renales se formaban mediante\u00a0procesos puramente qu\u00edmicos y f\u00edsicos: una acumulaci\u00f3n de cristales por saturaci\u00f3n de sustancias en la orina. Sin embargo, un estudio liderado por la Universidad de California en Los \u00c1ngeles (UCLA) y publicado esta semana en la revista PNAS acaba de […]<\/p>\n","protected":false},"author":5,"featured_media":0,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[5],"tags":[],"class_list":["post-196709","post","type-post","status-publish","format-standard","hentry","category-noticias"],"yoast_head":"\nLas bacterias podr\u00edan ser el andamio sobre el que se forman las piedras del ri\u00f1\u00f3n - bip4ex<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/helloproject.es\/vigilancia\/las-bacterias-podrian-ser-el-andamio-sobre-el-que-se-forman-las-piedras-del-rinon\/\" \/>\n<meta property=\"og:locale\" content=\"es_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Las bacterias podr\u00edan ser el andamio sobre el que se forman las piedras del ri\u00f1\u00f3n\" \/>\n<meta property=\"og:description\" content=\"Hasta ahora, la ciencia m\u00e9dica asum\u00eda que la mayor\u00eda de los c\u00e1lculos renales se formaban mediante\u00a0procesos puramente qu\u00edmicos y f\u00edsicos: una acumulaci\u00f3n de cristales por saturaci\u00f3n de sustancias en la orina. 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