{"id":204370,"date":"2026-05-21T09:28:06","date_gmt":"2026-05-21T08:28:06","guid":{"rendered":"https:\/\/helloproject.es\/vigilancia\/un-raton-capaz-de-regenerar-tejidos-evita-el-desarrollo-de-tumores\/"},"modified":"2026-05-21T09:28:06","modified_gmt":"2026-05-21T08:28:06","slug":"un-raton-capaz-de-regenerar-tejidos-evita-el-desarrollo-de-tumores","status":"publish","type":"post","link":"https:\/\/helloproject.es\/vigilancia\/un-raton-capaz-de-regenerar-tejidos-evita-el-desarrollo-de-tumores\/","title":{"rendered":"Un rat\u00f3n capaz de regenerar tejidos evita el desarrollo de tumores"},"content":{"rendered":"

Un equipo de investigaci\u00f3n del Instituto de Investigaciones Biom\u00e9dicas Sols-Morreale (IIBM-CSIC-UAM), en colaboraci\u00f3n con la Universidade do Algarve, ha demostrado que el rat\u00f3n espinoso africano (Acomys), conocido por su capacidad para regenerar tejidos complejos, presenta una notable resistencia al desarrollo de tumores.<\/p>\n


\n \"Logran
\n <\/a><\/p>\n

<\/a><\/p>\n

Logran eliminar tumores de p\u00e1ncreas en ratones por completo y sin que aparezcan resistencias<\/h3>\n

<\/p>\n


\n SINC
\n <\/a> <\/p>\n

A diferencia de la mayor\u00eda de los mam\u00edferos, que cicatrizan las heridas, este roedor es capaz de regenerar piel, m\u00fasculo e incluso restablecer conexiones funcionales en la m\u00e9dula espinal. Esta caracter\u00edstica lo ha convertido en un modelo clave para estudiar los mecanismos biol\u00f3gicos de la regeneraci\u00f3n.<\/p>\n

A diferencia de la mayor\u00eda de los mam\u00edferos, que cicatrizan las heridas, este roedor es capaz de regenerar piel, m\u00fasculo e incluso restablecer conexiones funcionales en la m\u00e9dula espinal<\/p>\n

Durante a\u00f1os, la comunidad cient\u00edfica ha comparado el c\u00e1ncer con \u201cuna herida que nunca cicatriza\u201d, ya que ambos procesos implican una intensa proliferaci\u00f3n celular. Esto ha llevado a plantear si los organismos con alta capacidad regenerativa podr\u00edan tener un mayor riesgo de desarrollar tumores.<\/p>\n

Sin embargo, los resultados del estudio apuntan en sentido contrario. Tras someter a los animales a un protocolo qu\u00edmico que induce tumores cut\u00e1neos, los ratones de laboratorio desarrollaron m\u00faltiples papilomas, mientras que los ratones espinosos no desarrollaron tumores.<\/p>\n

<\/a><\/p>\n

Genes supresores y defensa inmunitaria<\/h2>\n

El an\u00e1lisis molecular revel\u00f3 que Acomys activa de forma m\u00e1s intensa genes supresores de tumores, despliega una respuesta inmunitaria m\u00e1s amplia y elimina con mayor eficacia las c\u00e9lulas da\u00f1adas mediante muerte celular programada.<\/p>\n

<\/p>\n

Estos resultados indican que la regeneraci\u00f3n y la resistencia al c\u00e1ncer podr\u00edan estar estrechamente relacionadas<\/p>\n

Wolfgang Link, investigador del IIBM-CSIC
\n<\/p>\n

\u201cEstos resultados indican que la regeneraci\u00f3n y la resistencia al c\u00e1ncer podr\u00edan estar estrechamente relacionadas\u201d, explica Wolfgang Link, investigador del IIBM-CSIC. \u201cComprender estos mecanismos puede ayudar a identificar nuevas dianas terap\u00e9uticas\u201d.<\/p>\n

El trabajo sugiere que los procesos implicados en la regeneraci\u00f3n tisular podr\u00edan desempe\u00f1ar un papel clave en la prevenci\u00f3n del c\u00e1ncer, abriendo nuevas estrategias en oncolog\u00eda y medicina regenerativa.<\/p>\n

Referencia:<\/p>\n

Wolfgang Link et al. \u00abResistance to tumorigenesis in the african spiny mouse (Acomys) correlates with upregulation 8 of multiple tumor suppressor genes\u00bb. Scientific Reports<\/a>.<\/p>","protected":false},"excerpt":{"rendered":"

Un equipo de investigaci\u00f3n del Instituto de Investigaciones Biom\u00e9dicas Sols-Morreale (IIBM-CSIC-UAM), en colaboraci\u00f3n con la Universidade do Algarve, ha demostrado que el rat\u00f3n espinoso africano (Acomys), conocido por su capacidad para regenerar tejidos complejos, presenta una notable resistencia al desarrollo de tumores. Logran eliminar tumores de p\u00e1ncreas en ratones por completo y sin que aparezcan […]<\/p>\n","protected":false},"author":5,"featured_media":0,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[5],"tags":[],"class_list":["post-204370","post","type-post","status-publish","format-standard","hentry","category-noticias"],"yoast_head":"\nUn rat\u00f3n capaz de regenerar tejidos evita el desarrollo de tumores - bip4ex<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/helloproject.es\/vigilancia\/un-raton-capaz-de-regenerar-tejidos-evita-el-desarrollo-de-tumores\/\" \/>\n<meta property=\"og:locale\" content=\"es_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Un rat\u00f3n capaz de regenerar tejidos evita el desarrollo de tumores\" \/>\n<meta property=\"og:description\" content=\"Un equipo de investigaci\u00f3n del Instituto de Investigaciones Biom\u00e9dicas Sols-Morreale (IIBM-CSIC-UAM), en colaboraci\u00f3n con la Universidade do Algarve, ha demostrado que el rat\u00f3n espinoso africano (Acomys), conocido por su capacidad para regenerar tejidos complejos, presenta una notable resistencia al desarrollo de tumores. 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