{"id":211321,"date":"2026-10-30T20:28:25","date_gmt":"2026-10-30T19:28:25","guid":{"rendered":"https:\/\/helloproject.es\/vigilancia\/un-estudio-cartografia-como-se-propaga-el-virus-del-herpes-en-la-piel\/"},"modified":"2026-10-30T20:28:25","modified_gmt":"2026-10-30T19:28:25","slug":"un-estudio-cartografia-como-se-propaga-el-virus-del-herpes-en-la-piel","status":"publish","type":"post","link":"https:\/\/helloproject.es\/vigilancia\/un-estudio-cartografia-como-se-propaga-el-virus-del-herpes-en-la-piel\/","title":{"rendered":"Un estudio cartograf\u00eda c\u00f3mo se propaga el virus del herpes en la piel"},"content":{"rendered":"Investigadores del Centro Max Delbr\u00fcck y del Centro M\u00e9dico Universitario de Hamburgo-Eppendorf (Alemania) han estudiado en organoides cut\u00e1neos c\u00f3mo progresa el virus del herpes simple tipo 1 en las c\u00e9lulas de la piel. El trabajo se ha publicado en Science Advances.\nLa mayor\u00eda de la gente piensa que el virus del herpes\u00a0tipo 1 (VHS-1) es un solo un problema est\u00e9tico porque genera peque\u00f1as protuberancias en los labios o en la cara que suelen curarse por s\u00ed solas en el plazo de dos semanas. No obstante, esta infecci\u00f3n puede ser mucho m\u00e1s grave.\u00a0\nEste microorganismo infecta a las c\u00e9lulas nerviosas de la cara y permanece all\u00ed de forma latente\n                <a href=\"https:\/\/wa.me\/?text=\" title=\"Compartir en WhatsApp\"><\/a>\n                <a href=\"https:\/\/bsky.app\/intent\/compose?text=%3Cp%3EEste%20microorganismo%20infecta%20a%20las%20c%C3%A9lulas%20nerviosas%20de%20la%20cara%20y%20permanece%20all%C3%AD%20de%20forma%20latente%3C%2Fp%3E:+\" title=\"Compartir en BlueSky\"><\/a>\n                <a href=\"https:\/\/x.com\/intent\/tweet?url=&amp;via=agencia_sinc&amp;text=%3Cp%3EEste%20microorganismo%20infecta%20a%20las%20c%C3%A9lulas%20nerviosas%20de%20la%20cara%20y%20permanece%20all%C3%AD%20de%20forma%20latente%3C%2Fp%3E\" title=\"Compartir en X\"><\/a>\n                <a href=\"https:\/\/www.facebook.com\/sharer.php?u=&amp;t=%3Cp%3EEste%20microorganismo%20infecta%20a%20las%20c%C3%A9lulas%20nerviosas%20de%20la%20cara%20y%20permanece%20all%C3%AD%20de%20forma%20latente%3C%2Fp%3E\" title=\"Compartir en Facebook\"><\/a>\n                <a href=\"https:\/\/www.linkedin.com\/shareArticle?mini=true&amp;url=&amp;title=%3Cp%3EEste%20microorganismo%20infecta%20a%20las%20c%C3%A9lulas%20nerviosas%20de%20la%20cara%20y%20permanece%20all%C3%AD%20de%20forma%20latente%3C%2Fp%3E&amp;summary=%3Cp%3EEste%20microorganismo%20infecta%20a%20las%20c%C3%A9lulas%20nerviosas%20de%20la%20cara%20y%20permanece%20all%C3%AD%20de%20forma%20latente%3C%2Fp%3E&amp;source=agencia_sinc\" title=\"Compartir en LinkedIn\"><\/a>\n                <a href=\"http:\/\/www.agenciasinc.es\/Noticias\/un-estudio-cartografia-como-se-propaga-el-virus-del-herpes-en-la-piel#\" title=\"Copiar enlace\"><\/a>\n            (function () {\n                const copyText = text =&gt; navigator.clipboard\n                    ? navigator.clipboard.writeText(text)\n                    : new Promise((resolve, reject) =&gt; {\n                        try {\n                            const ta = document.createElement(&#8216;textarea&#8217;);\n                            ta.value = text;\n                            ta.setAttribute(&#8216;readonly&#8217;, \u00bb);\n                            ta.style.position = &#8216;absolute&#8217;;\n                            ta.style.left = &#8216;-9999px&#8217;;\n                            document.body.appendChild(ta);\n                            ta.select();\n                            document.execCommand(&#8216;copy&#8217;);\n                            document.body.removeChild(ta);\n                            resolve();\n                        } catch (e) { reject(e); }\n                    });\n                const showOk = el =&gt; {\n                    if (!el) return;\n                    el.classList.replace(&#8216;fa-link&#8217;, &#8216;fa-check&#8217;);\n                    const oldTitle = el.title;\n                    el.title = &#8216;URL copiada&#8217;;\n                    setTimeout(() =&gt; {\n                        el.classList.replace(&#8216;fa-check&#8217;, &#8216;fa-link&#8217;);\n                        el.title = oldTitle || &#8216;Copiar enlace&#8217;;\n                    }, 1600);\n                };\n                document.addEventListener(&#8216;click&#8217;, ev =&gt; {\n                    const t = ev.target;\n                    if (t?.classList?.contains(&#8216;copy-link&#8217;)) {\n                        ev.preventDefault();\n                        const url = t.getAttribute(&#8216;data-contenturl&#8217;) || window.location.href;\n                        copyText(url).then(() =&gt; showOk(t)).catch(() =&gt; showOk(t));\n                    }\n                });\n            })();\nDe hecho, este microorganismo infecta a las c\u00e9lulas nerviosas de la cara y permanece all\u00ed de forma latente. En casos muy excepcionales, puede desplazarse hasta el sistema nervioso central y provocar una inflamaci\u00f3n cerebral que ponga en peligro la vida. Adem\u00e1s, los expertos tambi\u00e9n est\u00e1n estudiando su posibles implicaciones en el desarrollo del alzh\u00e9imer.\nEl primer autor del trabajo e investigador del Max Delbr\u00fcck, Emanuel Wyler, lleva mucho tiempo interesado en desentra\u00f1ar el funcionamiento de este virus. Y, para ello, ha rastreado paso a paso c\u00f3mo infecta a las m\u00faltiples capas de c\u00e9lulas cut\u00e1neas mediante\u00a0organoides de piel humana con vello.\nLos investigadores han cartografiado c\u00f3mo se propaga el pat\u00f3geno y qu\u00e9 mol\u00e9culas de se\u00f1alizaci\u00f3n liberan las c\u00e9lulas a sus vecinas al ser infectadas. \u201cFue fascinante observar c\u00f3mo se propagaba el virus a trav\u00e9s del tejido organoide, de un tipo celular a otro, y tambi\u00e9n c\u00f3mo respond\u00eda\u00a0cada tipo celular al mismo\u00bb, expresa la l\u00edder del trabajo e investigadora en la misma instituci\u00f3n, Manja Czech-Sioli.\n\u00a0\n                        <a href=\"https:\/\/www.agenciasinc.es\/Reportajes\/El-alzheimer-una-enfermedad-infecciosa\">\n                            \n                        <\/a>\n                    <a href=\"https:\/\/www.agenciasinc.es\/Reportajes\/El-alzheimer-una-enfermedad-infecciosa\"><\/a>\n\n                            El alzh\u00e9imer, \u00bfuna enfermedad infecciosa?\n                        \n                    \n                                <a href=\"https:\/\/www.agenciasinc.es\/Autor\/Javier-Yanes\">\n                                    Javier Yanes\n                                <\/a>\nSeguimiento en una piel tridimensional\nLa piel humana tiene una estructura similar a la de un s\u00e1ndwich de varias capas, por lo que la l\u00e1mina\u00a0protectora m\u00e1s externa ser\u00eda la epidermis, compuesta principalmente por queratinocitos. Debajo se encontrar\u00eda la dermis, una capa de soporte rica en fibroblastos. Estos niveles\u00a0se ven atravesados por los fol\u00edculos que tambi\u00e9n contienen fibras nerviosas sensoriales.\nLos organoides cut\u00e1neos permitieron al equipo estudiar la infecci\u00f3n en un modelo tisular tridimensional complejo.\nLa piel humana tiene una estructura similar a la de un s\u00e1ndwich de varias capas\n                <a href=\"https:\/\/wa.me\/?text=\" title=\"Compartir en WhatsApp\"><\/a>\n                <a href=\"https:\/\/bsky.app\/intent\/compose?text=%3Cp%3ELa%20piel%20humana%20tiene%20una%20estructura%20similar%20a%20la%20de%20un%20s%C3%A1ndwich%20de%20varias%20capas%3C%2Fp%3E:+\" title=\"Compartir en BlueSky\"><\/a>\n                <a href=\"https:\/\/x.com\/intent\/tweet?url=&amp;via=agencia_sinc&amp;text=%3Cp%3ELa%20piel%20humana%20tiene%20una%20estructura%20similar%20a%20la%20de%20un%20s%C3%A1ndwich%20de%20varias%20capas%3C%2Fp%3E\" title=\"Compartir en X\"><\/a>\n                <a href=\"https:\/\/www.facebook.com\/sharer.php?u=&amp;t=%3Cp%3ELa%20piel%20humana%20tiene%20una%20estructura%20similar%20a%20la%20de%20un%20s%C3%A1ndwich%20de%20varias%20capas%3C%2Fp%3E\" title=\"Compartir en Facebook\"><\/a>\n                <a href=\"https:\/\/www.linkedin.com\/shareArticle?mini=true&amp;url=&amp;title=%3Cp%3ELa%20piel%20humana%20tiene%20una%20estructura%20similar%20a%20la%20de%20un%20s%C3%A1ndwich%20de%20varias%20capas%3C%2Fp%3E&amp;summary=%3Cp%3ELa%20piel%20humana%20tiene%20una%20estructura%20similar%20a%20la%20de%20un%20s%C3%A1ndwich%20de%20varias%20capas%3C%2Fp%3E&amp;source=agencia_sinc\" title=\"Compartir en LinkedIn\"><\/a>\n                <a href=\"http:\/\/www.agenciasinc.es\/Noticias\/un-estudio-cartografia-como-se-propaga-el-virus-del-herpes-en-la-piel#\" title=\"Copiar enlace\"><\/a>\n            (function () {\n                const copyText = text =&gt; navigator.clipboard\n                    ? navigator.clipboard.writeText(text)\n                    : new Promise((resolve, reject) =&gt; {\n                        try {\n                            const ta = document.createElement(&#8216;textarea&#8217;);\n                            ta.value = text;\n                            ta.setAttribute(&#8216;readonly&#8217;, \u00bb);\n                            ta.style.position = &#8216;absolute&#8217;;\n                            ta.style.left = &#8216;-9999px&#8217;;\n                            document.body.appendChild(ta);\n                            ta.select();\n                            document.execCommand(&#8216;copy&#8217;);\n                            document.body.removeChild(ta);\n                            resolve();\n                        } catch (e) { reject(e); }\n                    });\n                const showOk = el =&gt; {\n                    if (!el) return;\n                    el.classList.replace(&#8216;fa-link&#8217;, &#8216;fa-check&#8217;);\n                    const oldTitle = el.title;\n                    el.title = &#8216;URL copiada&#8217;;\n                    setTimeout(() =&gt; {\n                        el.classList.replace(&#8216;fa-check&#8217;, &#8216;fa-link&#8217;);\n                        el.title = oldTitle || &#8216;Copiar enlace&#8217;;\n                    }, 1600);\n                };\n                document.addEventListener(&#8216;click&#8217;, ev =&gt; {\n                    const t = ev.target;\n                    if (t?.classList?.contains(&#8216;copy-link&#8217;)) {\n                        ev.preventDefault();\n                        const url = t.getAttribute(&#8216;data-contenturl&#8217;) || window.location.href;\n                        copyText(url).then(() =&gt; showOk(t)).catch(() =&gt; showOk(t));\n                    }\n                });\n            })();\nMientras que los cultivos celulares planos revelan c\u00f3mo se comportan los virus en un solo tipo de c\u00e9lula, estos organoides conten\u00edan muchas de las caracter\u00edsticas de la piel humana real: c\u00e9lulas epid\u00e9rmicas, c\u00e9lulas d\u00e9rmicas, fol\u00edculos pilosos y c\u00e9lulas nerviosas. Por consiguiente, fueron un modelo muy adecuado para analizar c\u00f3mo progresaba la infecci\u00f3n por herpes tipo 1.\nSeg\u00fan explica Wyler a SINC, un organoide es una forma de reconstruir algunos aspectos de \u00f3rganos espec\u00edficos en un cultivo celular, es decir, en una placa de pl\u00e1stico. Hoy en d\u00eda existen para el cerebro, ri\u00f1ones e incluso la piel. \u201cSirven para reconstruir la estructura tridimensional del tejido, por lo que contienen varios tipos celulares diferentes, al igual que el original. Sin embargo, no son perfectos:\u00a0carecen de c\u00e9lulas inmunitarias, vasos sangu\u00edneos y, dado que maduran durante unos 4 meses, se asemejan m\u00e1s a una situaci\u00f3n fetal que a una adulta\u00bb, expone el cient\u00edfico.\u00a0\nEstos organoides se obtienen a partir de las llamadas c\u00e9lulas madre pluripotentes inducidas y proceden de donantes adultos voluntarios. El experto informa que, por lo general, se \u2018reprograman&#8217; para convertirse en cualquier tipo celular del cuerpo. La c\u00e9lula madre original pluripotente\u00a0es el \u00f3vulo fecundado, a partir del cual, durante el desarrollo embrionario\/ fetal se origina cada una de las c\u00e9lulas del cuerpo.\n\u201cLos organoides son una forma m\u00e1s eficiente de recrear una infecci\u00f3n en el cuerpo humano que la l\u00ednea celular \u2013frecuente en la investigaci\u00f3n biom\u00e9dica\u2013, que se desarrolla en una capa plana de c\u00e9lulas sobre pl\u00e1stico\u00bb, se\u00f1ala.\u00a0\n\u00a0\n                        <a href=\"https:\/\/www.agenciasinc.es\/Noticias\/Descubren-un-antiviral-contra-el-herpes-que-vence-la-resistencia-a-las-curas-actuales\">\n                            \n                        <\/a>\n                    <a href=\"https:\/\/www.agenciasinc.es\/Noticias\/Descubren-un-antiviral-contra-el-herpes-que-vence-la-resistencia-a-las-curas-actuales\"><\/a>\n\n                            Descubren un antiviral contra el herpes que vence la resistencia a las curas actuales\n                        \n                    \n                                <a href=\"https:\/\/www.agenciasinc.es\/Autor\/SINC,-SINC\">\n                                    SINC, SINC\n                                <\/a>\nReacci\u00f3n de c\u00e9lulas vecinas\nPor otro lado, el estudio\u00a0revel\u00f3\u00a0que el virus no infectaba a todos los elementos del tejido\u00a0de la misma manera. Por ejemplo, los fibroblastos de la dermis albergaban grandes cantidades de material v\u00edrico en las primeras fases de la infecci\u00f3n. En cambio, los queratinocitos basales, situados en la parte inferior de la epidermis, y varios tipos de c\u00e9lulas de los fol\u00edculos pilosos albergaban cantidades menores. De hecho, el pat\u00f3geno\u00a0no lleg\u00f3 a los fol\u00edculos pilosos ni a las neuronas sensoriales hasta m\u00e1s tarde, lo que indic\u00f3 que ambos tipos de c\u00e9lulas pod\u00edan tener cierta resistencia al virus.\nEl virus no infectaba a todos los elementos del tejido\u00a0de la misma manera\n                <a href=\"https:\/\/wa.me\/?text=\" title=\"Compartir en WhatsApp\"><\/a>\n                <a href=\"https:\/\/bsky.app\/intent\/compose?text=%3Cp%3EEl%20virus%20no%20infectaba%20a%20todos%20los%20elementos%20del%20tejido%C2%A0de%20la%20misma%20manera%3C%2Fp%3E:+\" title=\"Compartir en BlueSky\"><\/a>\n                <a href=\"https:\/\/x.com\/intent\/tweet?url=&amp;via=agencia_sinc&amp;text=%3Cp%3EEl%20virus%20no%20infectaba%20a%20todos%20los%20elementos%20del%20tejido%C2%A0de%20la%20misma%20manera%3C%2Fp%3E\" title=\"Compartir en X\"><\/a>\n                <a href=\"https:\/\/www.facebook.com\/sharer.php?u=&amp;t=%3Cp%3EEl%20virus%20no%20infectaba%20a%20todos%20los%20elementos%20del%20tejido%C2%A0de%20la%20misma%20manera%3C%2Fp%3E\" title=\"Compartir en Facebook\"><\/a>\n                <a href=\"https:\/\/www.linkedin.com\/shareArticle?mini=true&amp;url=&amp;title=%3Cp%3EEl%20virus%20no%20infectaba%20a%20todos%20los%20elementos%20del%20tejido%C2%A0de%20la%20misma%20manera%3C%2Fp%3E&amp;summary=%3Cp%3EEl%20virus%20no%20infectaba%20a%20todos%20los%20elementos%20del%20tejido%C2%A0de%20la%20misma%20manera%3C%2Fp%3E&amp;source=agencia_sinc\" title=\"Compartir en LinkedIn\"><\/a>\n                <a href=\"http:\/\/www.agenciasinc.es\/Noticias\/un-estudio-cartografia-como-se-propaga-el-virus-del-herpes-en-la-piel#\" title=\"Copiar enlace\"><\/a>\n            (function () {\n                const copyText = text =&gt; navigator.clipboard\n                    ? navigator.clipboard.writeText(text)\n                    : new Promise((resolve, reject) =&gt; {\n                        try {\n                            const ta = document.createElement(&#8216;textarea&#8217;);\n                            ta.value = text;\n                            ta.setAttribute(&#8216;readonly&#8217;, \u00bb);\n                            ta.style.position = &#8216;absolute&#8217;;\n                            ta.style.left = &#8216;-9999px&#8217;;\n                            document.body.appendChild(ta);\n                            ta.select();\n                            document.execCommand(&#8216;copy&#8217;);\n                            document.body.removeChild(ta);\n                            resolve();\n                        } catch (e) { reject(e); }\n                    });\n                const showOk = el =&gt; {\n                    if (!el) return;\n                    el.classList.replace(&#8216;fa-link&#8217;, &#8216;fa-check&#8217;);\n                    const oldTitle = el.title;\n                    el.title = &#8216;URL copiada&#8217;;\n                    setTimeout(() =&gt; {\n                        el.classList.replace(&#8216;fa-check&#8217;, &#8216;fa-link&#8217;);\n                        el.title = oldTitle || &#8216;Copiar enlace&#8217;;\n                    }, 1600);\n                };\n                document.addEventListener(&#8216;click&#8217;, ev =&gt; {\n                    const t = ev.target;\n                    if (t?.classList?.contains(&#8216;copy-link&#8217;)) {\n                        ev.preventDefault();\n                        const url = t.getAttribute(&#8216;data-contenturl&#8217;) || window.location.href;\n                        copyText(url).then(() =&gt; showOk(t)).catch(() =&gt; showOk(t));\n                    }\n                });\n            })();\nEn su investigaci\u00f3n, los autores combinaron las t\u00e9cnicas de imagen con la transcript\u00f3mica espacial\u00a0para medir la actividad g\u00e9nica en c\u00e9lulas individuales sin alterar su ubicaci\u00f3n en los tejidos. Esto les permiti\u00f3 estudiar el frente de la infecci\u00f3n \u2014la zona donde el herpes tipo 1 acababa de llegar a las nuevas c\u00e9lulas\u2014 e identificar qu\u00e9 genes se activaban.\nAqu\u00ed los fibroblastos d\u00e9rmicos activaron\u00a0el IER3 \u2013un gen conocido por responder al virus\u2013, y los queratinocitos basales aumentaron la expresi\u00f3n del IRF3, un regulador de las defensas antivirales. Tambi\u00e9n descubrieron que los miembros de la familia de mol\u00e9culas de se\u00f1alizaci\u00f3n del factor de necrosis tumoral (TNF) se activaron\u00a0de manera espacialmente coordinada.\nLos futuros modelos de organoides que incluyan c\u00e9lulas inmunitarias y vasos sangu\u00edneos podr\u00edan ayudar a los investigadores a estudiar c\u00f3mo el organismo controla el herpes antes de que llegue a los nervios, adem\u00e1s de entender por qu\u00e9 algunas c\u00e9lulas frenan el virus mientras que otras favorecen su replicaci\u00f3n.\nReferencia:\nWyler. E. et al. Human Hair-Bearing Skin Organoids reveal Cell Type Specific Susceptibility and Innate Immune Responses to Herpes Simplex Virus 1. <a href=\"http:\/\/dx.doi.org\/10.1126\/sciadv.aef5563\" title=\"\">Science Advances<\/a>\u00a02026.","protected":false},"excerpt":{"rendered":"<p>Investigadores del Centro Max Delbr\u00fcck y del Centro M\u00e9dico Universitario de Hamburgo-Eppendorf (Alemania) han estudiado en organoides cut\u00e1neos c\u00f3mo progresa el virus del herpes simple tipo 1 en las c\u00e9lulas de la piel. El trabajo se ha publicado en Science Advances. La mayor\u00eda de la gente piensa que el virus del herpes\u00a0tipo 1 (VHS-1) es [&hellip;]<\/p>\n","protected":false},"author":5,"featured_media":0,"comment_status":"","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[5],"tags":[],"class_list":["post-211321","post","type-post","status-publish","format-standard","hentry","category-noticias"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v20.9 (Yoast SEO v28.8) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Un estudio cartograf\u00eda c\u00f3mo se propaga el virus del herpes en la piel - bip4ex<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/helloproject.es\/vigilancia\/un-estudio-cartografia-como-se-propaga-el-virus-del-herpes-en-la-piel\/\" \/>\n<meta property=\"og:locale\" content=\"es_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Un estudio cartograf\u00eda c\u00f3mo se propaga el virus del herpes en la piel\" \/>\n<meta property=\"og:description\" content=\"Investigadores del Centro Max Delbr\u00fcck y del Centro M\u00e9dico Universitario de Hamburgo-Eppendorf (Alemania) han estudiado en organoides cut\u00e1neos c\u00f3mo progresa el virus del herpes simple tipo 1 en las c\u00e9lulas de la piel. El trabajo se ha publicado en Science Advances. 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