{"id":74708,"date":"2025-03-07T08:28:03","date_gmt":"2025-03-07T07:28:03","guid":{"rendered":"https:\/\/helloproject.es\/vigilancia\/el-gen-responsable-de-la-obesidad-el-mismo-en-labradores-y-humanos\/"},"modified":"2025-03-07T08:28:03","modified_gmt":"2025-03-07T07:28:03","slug":"el-gen-responsable-de-la-obesidad-el-mismo-en-labradores-y-humanos","status":"publish","type":"post","link":"https:\/\/helloproject.es\/vigilancia\/el-gen-responsable-de-la-obesidad-el-mismo-en-labradores-y-humanos\/","title":{"rendered":"El gen responsable de la obesidad, el mismo en labradores y humanos"},"content":{"rendered":"<p>Un estudio de la Universidad de Cambridge (Reino Unido) revela importantes hallazgos sobre la gen\u00e9tica de la obesidad en perros y su relaci\u00f3n con la enfermedad humana. La investigaci\u00f3n, <a href=\"https:\/\/dx.doi.org\/10.1126\/science.ads2145\" target=\"_blank\">publicada en la revista Science<\/a>, se centra en labradores retriever brit\u00e1nicos e identifica m\u00faltiples genes asociados con la patolog\u00eda canina que tambi\u00e9n est\u00e1n vinculados a la que se da en humanos.<\/p>\n<p>El\u00a0gen DENND1B\u00a0es el m\u00e1s fuertemente asociado con la obesidad en los labradores. Tambi\u00e9n presente en humanos, est\u00e1 relacionado con la patolog\u00eda en personas<\/p>\n<p>Seg\u00fan el estudio, el gen DENND1B es el m\u00e1s fuertemente asociado con la obesidad en los labradores. Los investigadores descubrieron que este, tambi\u00e9n presente en humanos, est\u00e1 relacionado con la patolog\u00eda en personas. Adem\u00e1s, afecta directamente una v\u00eda cerebral, responsable de regular el equilibrio energ\u00e9tico en el cuerpo, conocida como la v\u00eda de la leptina melanocortina.<\/p>\n<p>Alyce McClellan, autora principal del trabajo, explica que, aunque estos genes no son objetivos inmediatos para medicamentos para perder peso debido a su participaci\u00f3n en otros procesos biol\u00f3gicos clave, los resultados enfatizan la importancia de las v\u00edas cerebrales fundamentales en el control del apetito y el peso corporal.<\/p>\n<p><a><\/a><\/p>\n<h2>Pedir comida a los due\u00f1os<\/h2>\n<p>Los investigadores tambi\u00e9n han observado que los perros con alto riesgo gen\u00e9tico de obesidad muestran mayor inter\u00e9s en la comida. Natalie Wallis, otra autora principal, se\u00f1ala que midieron cu\u00e1nto molestaban los perros a sus due\u00f1os por comida y si eran quisquillosos con la alimentaci\u00f3n.<\/p>\n<p>Los investigadores tambi\u00e9n han observado que los perros con alto riesgo gen\u00e9tico de obesidad muestran mayor inter\u00e9s en la comida<\/p>\n<p>As\u00ed, los perros con alto riesgo gen\u00e9tico de obesidad mostraron signos de tener mayor apetito, similar a lo observado en personas con el mismo alto riesgo de la enfermedad. De hecho, los due\u00f1os que controlaban estrictamente la dieta y el ejercicio de sus canes lograban prevenir esta condici\u00f3n incluso en aquellos con gran peligro, aunque requer\u00eda mucha m\u00e1s atenci\u00f3n y esfuerzo.<\/p>\n<p>De manera similar, las personas con alto riesgo gen\u00e9tico de desarrollar obesidad no necesariamente se volver\u00e1n obesas si siguen una dieta estricta y un r\u00e9gimen de ejercicios, pero son m\u00e1s propensas a ganar peso.<\/p>\n<p><a><\/a><\/p>\n<h2>Distribuir la raci\u00f3n diaria de comida<\/h2>\n<p>Para disminuir la obesidad en estos perros, los investigadores sugieren distribuir las raciones diarias de comida<\/p>\n<p>Eleanor Raffan, l\u00edder del estudio, enfatiza que los resultados demuestran que los due\u00f1os de perros delgados no son \u201cmoralmente superiores\u201d, al igual que las personas delgadas. Si se tiene un alto riesgo gen\u00e9tico de obesidad, se es propenso a comer en exceso y ganar peso cuando hay mucha comida disponible, a menos que se haga un gran esfuerzo para evitarlo, puntualiza.<\/p>\n<p>Para disminuir la obesidad en estos perros, los investigadores sugieren distribuir las raciones diarias de comida, utilizando comederos de rompecabezas o eligiendo una composici\u00f3n de nutrientes m\u00e1s satisfactoria para sus mascotas.<\/p>\n<p>Referencia:<\/p>\n<p>Natalie J. Wallis et al.: \u2018Canine genome-wide association study identifies DENND1B as an obesity gene in dogs and humans\u2019. <a href=\"https:\/\/dx.doi.org\/10.1126\/science.ads2145\" target=\"_blank\">Science<\/a> (2025)<\/p>","protected":false},"excerpt":{"rendered":"<p>Un estudio de la Universidad de Cambridge (Reino Unido) revela importantes hallazgos sobre la gen\u00e9tica de la obesidad en perros y su relaci\u00f3n con la enfermedad humana. La investigaci\u00f3n, publicada en la revista Science, se centra en labradores retriever brit\u00e1nicos e identifica m\u00faltiples genes asociados con la patolog\u00eda canina que tambi\u00e9n est\u00e1n vinculados a la [&hellip;]<\/p>\n","protected":false},"author":5,"featured_media":0,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[5],"tags":[],"class_list":["post-74708","post","type-post","status-publish","format-standard","hentry","category-noticias"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v20.9 (Yoast SEO v27.7) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>El gen responsable de la obesidad, el mismo en labradores y humanos - bip4ex<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/helloproject.es\/vigilancia\/el-gen-responsable-de-la-obesidad-el-mismo-en-labradores-y-humanos\/\" \/>\n<meta property=\"og:locale\" content=\"es_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"El gen responsable de la obesidad, el mismo en labradores y humanos\" \/>\n<meta property=\"og:description\" content=\"Un estudio de la Universidad de Cambridge (Reino Unido) revela importantes hallazgos sobre la gen\u00e9tica de la obesidad en perros y su relaci\u00f3n con la enfermedad humana. 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