{"id":87398,"date":"2025-03-26T08:28:20","date_gmt":"2025-03-26T07:28:20","guid":{"rendered":"https:\/\/helloproject.es\/vigilancia\/describen-la-bombesina-una-antigua-neurohormona-que-controla-el-apetito\/"},"modified":"2025-03-26T08:28:20","modified_gmt":"2025-03-26T07:28:20","slug":"describen-la-bombesina-una-antigua-neurohormona-que-controla-el-apetito","status":"publish","type":"post","link":"https:\/\/helloproject.es\/vigilancia\/describen-la-bombesina-una-antigua-neurohormona-que-controla-el-apetito\/","title":{"rendered":"Describen la \u2018bombesina\u2019, una antigua neurohormona que controla el apetito"},"content":{"rendered":"

Una neurohormona que controla el apetito en humanos tiene, en realidad, un antiguo origen evolutivo, que se remonta a m\u00e1s de 500 millones de a\u00f1os y podr\u00eda ayudar al desarrollo de nuevos f\u00e1rmacos para adelgazar.<\/p>\n

La mol\u00e9cula, denominada\u00a0bombesina,\u00a0induce la saciedad en humanos, en otros vertebrados y tambi\u00e9n en estrellas de mar y sus parientes marinos, seg\u00fan un estudio encabezado por bi\u00f3logos de la Universidad Queen Mary (Reino Unido) que publica PNAS.<\/p>\n

Aislado por primera vez en 1971 en la piel de un sapo de vientre fuego, este p\u00e9ptido reduce la ingesta de comida y aumenta el tiempo entre tomas cuando se inyecta en mam\u00edferos<\/p>\n

Este p\u00e9ptido fue aislado por primera vez en la piel de un sapo de vientre fuego (Bombina bombina) en 1971 y posteriores investigaciones mostraron que, cuando se inyecta en mam\u00edferos, reduce la cantidad ingerida en cada comida y aumenta el tiempo entre tomas.<\/p>\n

Esto llev\u00f3 a los cient\u00edficos a creer que las neurohormonas similares a la\u00a0bombesina, producidas en el cerebro y el intestino, forman parte del\u00a0sistema natural del organismo para controlar la ingesta de alimentos.<\/p>\n

<\/a><\/p>\n

Historia evolutiva\u00a0<\/h2>\n

El equipo se propuso explorar la historia evolutiva de la\u00a0bombesina, para lo que analizaron los genomas de animales invertebrados y descubrieron genes que codifican neurohormonas similares en la estrella de mar com\u00fan (Asterias rubens) y otros equinodermos, como erizos y pepinos de mar.<\/p>\n

Los investigadores centraron su atenci\u00f3n en la funci\u00f3n de esta\u00a0bombesina\u00a0de estrella de mar, denominada ArBN, para lo que la sintetizaron qu\u00edmicamente y la sometieron a pruebas.<\/p>\n

Las estrellas de mar sacan el est\u00f3mago de la boca para digerir presas como mejillones y ostras, pero al inyectar ArBN en ejemplares con el est\u00f3mago evertido, este se retrajo hacia la boca y se retras\u00f3 el inicio de la alimentaci\u00f3n.<\/p>\n

El descubrimiento del papel de la\u00a0bombesina\u00a0en la regulaci\u00f3n del apetito arroja luz sobre los or\u00edgenes evolutivos del comportamiento alimentario en animales<\/p>\n

El descubrimiento del antiguo papel de la\u00a0bombesina\u00a0en la regulaci\u00f3n del apetito arroja luz sobre los or\u00edgenes evolutivos del comportamiento alimentario en los animales.<\/p>\n

<\/a><\/p>\n

Ancestro com\u00fan\u00a0<\/h2>\n

\u201cPodemos deducir que esta funci\u00f3n se remonta 500 millones de a\u00f1os atr\u00e1s, hasta el ancestro com\u00fan de las estrellas de mar, los humanos y otros vertebrados\u201d, seg\u00fan Maurice Elphick, de la\u00a0 universidad brit\u00e1nica y uno de los firmantes del estudio.<\/p>\n

Este descubrimiento puede tener aplicaciones pr\u00e1cticas en el contexto del cambio clim\u00e1tico, pues debido al mismo \u00abalgunas especies de estrellas de mar est\u00e1n invadiendo aguas m\u00e1s fr\u00edas donde se cultivan moluscos para el consumo humano\u201d.<\/p>\n

Por ello, agreg\u00f3 que \u201cdescubrir mol\u00e9culas que inhiban la alimentaci\u00f3n en las estrellas de mar podr\u00eda ser \u00fatil para gestionar estas invasiones\u201d.<\/p>","protected":false},"excerpt":{"rendered":"

Una neurohormona que controla el apetito en humanos tiene, en realidad, un antiguo origen evolutivo, que se remonta a m\u00e1s de 500 millones de a\u00f1os y podr\u00eda ayudar al desarrollo de nuevos f\u00e1rmacos para adelgazar. La mol\u00e9cula, denominada\u00a0bombesina,\u00a0induce la saciedad en humanos, en otros vertebrados y tambi\u00e9n en estrellas de mar y sus parientes marinos, […]<\/p>\n","protected":false},"author":5,"featured_media":0,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[5],"tags":[],"class_list":["post-87398","post","type-post","status-publish","format-standard","hentry","category-noticias"],"yoast_head":"\nDescriben la \u2018bombesina\u2019, una antigua neurohormona que controla el apetito - bip4ex<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/helloproject.es\/vigilancia\/describen-la-bombesina-una-antigua-neurohormona-que-controla-el-apetito\/\" \/>\n<meta property=\"og:locale\" content=\"es_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Describen la \u2018bombesina\u2019, una antigua neurohormona que controla el apetito\" \/>\n<meta property=\"og:description\" content=\"Una neurohormona que controla el apetito en humanos tiene, en realidad, un antiguo origen evolutivo, que se remonta a m\u00e1s de 500 millones de a\u00f1os y podr\u00eda ayudar al desarrollo de nuevos f\u00e1rmacos para adelgazar. 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